Serzone and Lupron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Lupron (leuprolide acetate). Common drug interactions include thyroid disorder among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Lupron. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.

On Jul, 08, 2026

19 people who take Serzone and Lupron together, and have interactions are studied.

What are the common drug interactions of Serzone and Lupron, by gender? *:

female:

Thyroid disorder (thyroid diseases)
Thyrotoxicosis (a morbid condition due to over activity of the thyroid gland)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight decreased
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Headache (pain in head)
Heart rate increased
Hot flushes (sudden feelings of heat)

male:

Chest pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Enteritis (inflammation of the small intestine)
Erectile dysfunction
Fatigue (feeling of tiredness)
Gastroenteritis radiation (radiation induced inflammation of stomach and intestine)
Haemoglobin decreased

What are the common drug interactions of Serzone and Lupron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Grand mal convulsion (a type of generalized seizure that affects the entire brain)

40-49:

Tremor (trembling or shaking movements in one or more parts of your body)
Weight decreased
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Heart rate increased
Hot flushes (sudden feelings of heat)
Insomnia (sleeplessness)
Oedema (fluid collection in tissue)
Thyroid disorder (thyroid diseases)
Thyrotoxicosis (a morbid condition due to over activity of the thyroid gland)

50-59:

Hypochromic anaemia (hypochromic anaemia is a generic term for any type of anaemia in which the red blood cells (erythrocytes) are paler than normal)
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)

60+:

Chest pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Enteritis (inflammation of the small intestine)
Erectile dysfunction
Fatigue (feeling of tiredness)
Gastroenteritis radiation (radiation induced inflammation of stomach and intestine)
Haemoglobin decreased

What are the existing conditions these people have? *

Prostate Cancer: 14 people, 73.68%
Pain: 14 people, 73.68%
Bone Density Abnormal: 14 people, 73.68%
Uterine Fibroids (benign growths of the muscle inside the uterus): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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