Serzone and Niaspan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Niaspan (niacin). Common drug interactions include colitis ischaemic among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Niaspan. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

On Jul, 14, 2026

39 people who take Serzone and Niaspan together, and have interactions are studied.

What are the common drug interactions of Serzone and Niaspan, by gender? *:

female:

Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Deafness transitory (deafness temporary)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Glossitis (infection of tongue with soreness)
Haematochezia (passage of stools containing blood)
Headache (pain in head)
Hypersensitivity
Influenza like illness
Nausea (feeling of having an urge to vomit)

male:

Emotional distress
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain upper
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac valve abscess (pus containing infection of heart valve)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)

What are the common drug interactions of Serzone and Niaspan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls)

40-49:

Flushing (the warm, red condition of human skin)
Influenza like illness
Abdominal pain
Application site vesicles (small bubble within a cell at application site)
Asthenia (weakness)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Dizziness
Fatigue (feeling of tiredness)
Haematochezia (passage of stools containing blood)
Headache (pain in head)

50-59:

Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardiac valve abscess (pus containing infection of heart valve)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Conjunctivitis (pink eye)
Constipation
Corneal abrasion (loss of the surface of cornea)
Decreased interest
Deformity (disfigurement)

60+:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Anaemia (lack of blood)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Aortic valve replacement
Aphasia (damage to the parts of the brain that control language)
Arteriosclerosis (thickening and hardening of arteries)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthenia (weakness)
Balance disorder

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 11 people, 28.21%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 15.38%
Headache (pain in head): 6 people, 15.38%
High Blood Pressure: 5 people, 12.82%
Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 10.26%
Joint Pain: 4 people, 10.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.26%
Diabetes: 4 people, 10.26%
Insomnia (sleeplessness): 2 people, 5.13%
Dizziness: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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