Serzone and Ranitidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Ranitidine (ranitidine). Common drug interactions include hypercholesterolaemia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Ranitidine. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

On Jul, 15, 2026

68 people who take Serzone and Ranitidine together, and have interactions are studied.

Serzone and Ranitidine drug interactions.

What are the common drug interactions of Serzone and Ranitidine, by gender? *:

female:

Hypercholesterolaemia (high levels of cholesterol in the blood)
Hyperglycaemia (high blood sugar)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pleural effusion (water on the lungs)
Accidental exposure
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Balance disorder

male:

Abdominal pain
Dystonia (abnormal muscle tone)
Peripheral neuropathy (damage to nerves of the peripheral nervous system)
Tremor (trembling or shaking movements in one or more parts of your body)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug ineffective
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Flatulence (flatus expelled through the anus)
Hepatotoxicity (chemical-driven liver damage)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Serzone and Ranitidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Muscle twitching
Tremor (trembling or shaking movements in one or more parts of your body)
Asterixis (flapping tremor, or liver flap)
Balance disorder
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Psychomotor retardation (motor mental retardation)
Venous angioma of brain (benign tumour in the brain)

30-39:

Nausea (feeling of having an urge to vomit)
Dystonia (abnormal muscle tone)
Overdose
Accidental exposure
Atelectasis (partial or complete collapse of the lung)
Blood creatinine increased
Blood glucose increased
Blood potassium decreased
Brain injury
Burns first degree

40-49:

Hepatitis (inflammation of the liver)
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Abdominal pain
Weight decreased
Epistaxis (bleed from the nose)
Hypotension (abnormally low blood pressure)
Pancreatitis (inflammation of pancreas)
Peripheral neuropathy (damage to nerves of the peripheral nervous system)
Vomiting
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)

50-59:

Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Plica syndrome (painful impairment of knee function)
Polyp
Renal failure (kidney dysfunction)
Rhinorrhoea (watery mucus discharge from the nose)
Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)

60+:

Chronic kidney disease
Asthenia (weakness)
Pain
Pain in extremity
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Tardive dyskinesia (a disorder that involves involuntary movements)
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal discomfort
Abdominal distension

What are the existing conditions these people have? *

Pain: 14 people, 20.59%
Cardiac Disorder: 11 people, 16.18%
Diabetes: 10 people, 14.71%
Sleep Disorder: 9 people, 13.24%
Nausea (feeling of having an urge to vomit): 9 people, 13.24%
Insomnia (sleeplessness): 8 people, 11.76%
Stress And Anxiety: 8 people, 11.76%
Gastric Ulcer (stomach ulcer): 7 people, 10.29%
Fluid Retention (an abnormal accumulation of fluid in the blood): 6 people, 8.82%
Asthma: 6 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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