Simvastatin and Cosopt pf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Cosopt pf (dorzolamide hydrochloride; timolol maleate). Common drug interactions include chronic kidney disease among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Cosopt pf. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

What is Cosopt pf?

Cosopt pf has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 1,989 Cosopt pf users. Check the latest studies of Cosopt pf.

On Jul, 26, 2026

15 people who take Simvastatin and Cosopt pf together, and have interactions are studied.

Simvastatin and Cosopt pf drug interactions.

What are the common drug interactions of Simvastatin and Cosopt Pf, by gender? *:

female:

Chronic kidney disease
Eyelid injury
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Death

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Parkinson's disease
Presyncope
Swelling face
Blepharitis (chronic inflammation of the eyelid)
Cardiac failure congestive
Death
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Eye irritation
Eyelid oedema (eyelids are swollen and contain excessive fluid)

What are the common drug interactions of Simvastatin and Cosopt Pf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Arthralgia (joint pain)
Asthenia (weakness)
Neck pain
Ocular hyperaemia (an abnormally large amount of blood in eye)
Presyncope
Swelling face
Vision blurred
Back pain
Blepharitis (chronic inflammation of the eyelid)
Death

What are the existing conditions these people have? *

Stress And Anxiety: 1 person, 6.67%
Prostate Cancer: 1 person, 6.67%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 6.67%
Anaemia (lack of blood): 1 person, 6.67%
Birth Control: 1 person, 6.67%
Blood Phosphorus Decreased: 1 person, 6.67%
Constipation: 1 person, 6.67%
Depression: 1 person, 6.67%
Diabetes: 1 person, 6.67%
Dry Eyes (lack of adequate tears): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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