Simvastatin and Plegridy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Plegridy (peginterferon beta-1a). Common drug interactions include pneumonia bacterial among females and influenza like illness among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Plegridy. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

What is Plegridy?

Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.

On Jul, 12, 2026

96 people who take Simvastatin and Plegridy together, and have interactions are studied.

Simvastatin and Plegridy drug interactions.

What are the common drug interactions of Simvastatin and Plegridy, by gender? *:

female:

Pneumonia bacterial (pneumonia associated with bacterial infection)
Postoperative wound complication
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Ankle fracture
Breast cancer
Cystitis (inflammation of the wall of the bladder)
Dizziness
Mobility decreased (ability to move is reduced)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Balance disorder

male:

Influenza like illness
Injection site erythema (redness at injection site)
Road traffic accident
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation
Death
Diarrhoea
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Injection site inflammation

What are the common drug interactions of Simvastatin and Plegridy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

Pain
Asthenia (weakness)
Blindness
Chest pain
Chills (felling of cold)
Crest syndrome (thick, dry and fibrous skin)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)
Gastric antral vascular ectasia (blood vessels in the lining of the stomach become fragile and become prone to rupture and bleeding)

50-59:

Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Muscular weakness (muscle weakness)
Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
Nausea (feeling of having an urge to vomit)
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Postmenopausal haemorrhage (post-menopausal bleeding)
Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina)

60+:

Hypoacusis (loss of hearing)
Influenza like illness
Herpes zoster
Iron deficiency anaemia
Leukocytosis (increased white blood cells)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pleural effusion (water on the lungs)
Pneumonia

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 90 people, 93.75%
High Blood Pressure: 9 people, 9.38%
Gait Disturbance: 8 people, 8.33%
Muscle Spasms (muscle contraction): 7 people, 7.29%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 6.25%
Diabetes: 6 people, 6.25%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 5.21%

* Approximation only. Some reports may have incomplete information.

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