Synthroid and Estradiol valerate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synthroid (levothyroxine sodium) and Estradiol valerate (estradiol valerate). Common drug interactions include atrial fibrillation among females.

The phase IV clinical study analyzes what interactions people have when they take Synthroid and Estradiol valerate. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.

What is Estradiol valerate?

Estradiol valerate has active ingredients of estradiol valerate. eHealthMe is studying from 347 Estradiol valerate users. Check the latest studies of Estradiol valerate.

On Jul, 09, 2026

26 people who take Synthroid and Estradiol valerate together, and have interactions are studied.

Synthroid and Estradiol valerate drug interactions.

What are the common drug interactions of Synthroid and Estradiol Valerate, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Abdominal pain
Fatigue (feeling of tiredness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Weight increased
Bacterial infection
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Contusion (a type of hematoma of tissue in which capillaries)
Cough

male:

n/a

What are the common drug interactions of Synthroid and Estradiol Valerate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hypokalaemia (low potassium)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Eyelid pain
Headache (pain in head)
Pneumonia

50-59:

n/a

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Abdominal pain
Fatigue (feeling of tiredness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Bacterial infection
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dysphonia (speech disorder attributable to a disorder of phonation)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 61.54%
High Blood Cholesterol: 7 people, 26.92%
Breast Cancer: 3 people, 11.54%
Multiple Myeloma (cancer of the plasma cells): 3 people, 11.54%
Stress And Anxiety: 2 people, 7.69%
Cough: 2 people, 7.69%
Diarrhea: 2 people, 7.69%
Folate Deficiency (lack of folic acid): 2 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
Herpes Zoster: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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