Tecfidera and Bisacodyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tecfidera (dimethyl fumarate) and Bisacodyl (bisacodyl). Common drug interactions include musculoskeletal stiffness among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Tecfidera and Bisacodyl. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Bisacodyl?

Bisacodyl has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 18,852 Bisacodyl users. Check the latest studies of Bisacodyl.



On Jul, 25, 2026

79 people who take Tecfidera and Bisacodyl together, and have interactions are studied.

Tecfidera and Bisacodyl drug interactions.

What are the common drug interactions of Tecfidera and Bisacodyl, by gender? *:

female:

  1. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  2. Neck pain
  3. Neuralgia (pain in one or more nerves)
  4. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  5. Oral herpes (viral infection of mouth)
  6. Oropharyngeal pain
  7. Piloerection (goose bumps)
  8. Sinusitis (inflammation of sinus)
  9. Skin disorder (skin disease)
  10. Sleep disorder

male:

  1. Flushing (the warm, red condition of human skin)
  2. Asthenia (weakness)
  3. Death
  4. Irritability
  5. Pain
  6. Cellulitis (infection under the skin)
  7. Mobility decreased (ability to move is reduced)
  8. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  9. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  10. Ear infection

What are the common drug interactions of Tecfidera and Bisacodyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cellulitis (infection under the skin)
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  4. Death
  5. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  6. Neuralgia (pain in one or more nerves)
  7. Progressive multiple sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord)
  8. Transaminases increased
  9. Urinary tract infection

40-49:

  1. Oesophageal carcinoma (cancer tumour of oesophagus)
  2. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  3. Irritable bowel syndrome
  4. Upper-airway cough syndrome
  5. Flushing (the warm, red condition of human skin)
  6. Urinary tract infection
  7. Asthenia (weakness)
  8. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  9. Dysstasia (difficulty in standing)
  10. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

50-59:

  1. Upper-airway cough syndrome
  2. Balance disorder
  3. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  4. Fall
  5. Femur fracture
  6. Quadriparesis (muscle weakness affecting all four limbs)
  7. Abdominal pain
  8. Abdominal pain upper
  9. Aggression
  10. Breast cancer

60+:

  1. Abdominal distension
  2. Diarrhoea
  3. Metapneumovirus infection (infection with human metapneumovirus)
  4. Muscular weakness (muscle weakness)
  5. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  6. Pneumonia viral
  7. Respiratory distress (difficulty in breathing)
  8. Staphylococcal infection (an infection with staphylococcus bacteria)
  9. Agitation (state of anxiety or nervous excitement)
  10. Irritability

What are the existing conditions these people have? *

  1. Pain: 12 people, 15.19%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 9 people, 11.39%
  3. Chest Pain: 5 people, 6.33%
  4. Sleep Disorder: 4 people, 5.06%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 5.06%
  6. Hypersensitivity: 4 people, 5.06%
  7. Dyspnea (difficult or laboured breathing): 4 people, 5.06%
  8. Depression: 4 people, 5.06%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tecfidera and Bisacodyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tecfidera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bisacodyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tecfidera and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bisacodyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dimethyl fumarate and bisacodyl (the active ingredients of Tecfidera and Bisacodyl, respectively), and Tecfidera and Bisacodyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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