Tenex and Coreg drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tenex (guanfacine hydrochloride) and Coreg (carvedilol). Common drug interactions include back pain among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Tenex and Coreg. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Tenex?

Tenex has active ingredients of guanfacine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,865 Tenex users. Check the latest studies of Tenex.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.

On Jul, 13, 2026

32 people who take Tenex and Coreg together, and have interactions are studied.

What are the common drug interactions of Tenex and Coreg, by gender? *:

female:

Back pain
Bleeding time prolonged
Blood glucose increased
Blood urea increased
Cardiovascular disorder (heart diseases)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cytomegalovirus infection
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

male:

Depression
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood potassium decreased
Cardiac disorder
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Emotional distress
Fear
Haematological malignancy (cancer that affect blood, bone marrow, and lymph nodes)

What are the common drug interactions of Tenex and Coreg, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Nervous system disorder (a general class of medical conditions affecting the nervous system)
Visual impairment

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Lethargy (tiredness)
Pain in extremity
Postoperative wound infection
Renal impairment (severely reduced kidney function)
Blood potassium decreased
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

50-59:

Injection site mass
Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Injection site pain
Neuropathy peripheral (surface nerve damage)
Nipple infection
Orthopnoea (shortness of breath (dyspnea) when lying down)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Renal cancer (cancer of kidney)
Weight decreased
Cardiac disorder

60+:

Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood iron decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 5 people, 15.62%
Depression: 5 people, 15.62%
Pain: 3 people, 9.38%
High Blood Cholesterol: 3 people, 9.38%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 9.38%
Sleep Disorder: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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