Tenormin and Tysabri drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tenormin (atenolol) and Tysabri (natalizumab). Common drug interactions include paraesthesia among females and progressive multifocal leukoencephalopathy among males.
The phase IV clinical study analyzes what interactions people have when they take Tenormin and Tysabri. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Tenormin?
Tenormin has active ingredients of atenolol. It is often used in high blood pressure. eHealthMe is studying from 20,474 Tenormin users. Check the latest studies of Tenormin.
What is Tysabri?
Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.
32 people who take Tenormin and Tysabri together, and have interactions are studied.

What are the common drug interactions of Tenormin and Tysabri, by gender? *:
female:
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Peroneal nerve palsy
- Muscular weakness (muscle weakness)
- Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
- Vomiting
- Malaise (a feeling of general discomfort or uneasiness)
- Back pain
- Concussion (short loss of normal brain function in response to a head injury)
- Fatigue (feeling of tiredness)
- Pain
male:
- Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
- Osteoporosis (bones weak and more likely to break)
- Balance disorder
- Gait disturbance
- Nausea (feeling of having an urge to vomit)
- Neuralgia (pain in one or more nerves)
- Weight decreased
- Anaemia (lack of blood)
- Bone density decreased
- Bone disorder
What are the common drug interactions of Tenormin and Tysabri, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
30-39:
- Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
- Anaemia (lack of blood)
- Decreased appetite
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diplopia (double vision)
- Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
- Dysgeusia (disorder of the sense of taste)
- Eosinophil count increased
- Eyelid ptosis (falling of the upper or lower eyelid)
- Malaise (a feeling of general discomfort or uneasiness)
40-49:
- Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
- Urinary tract infection
- Vomiting
- Anxiety
- Muscle spasms (muscle contraction)
- Nausea (feeling of having an urge to vomit)
- Stress
- Pain
- Aortic disorder
- Aphasia (damage to the parts of the brain that control language)
50-59:
- Photophobia (extreme sensitivity to light)
- Pleural fibrosis (formation of fibrous tissue in lung)
- Post laminectomy syndrome
- Prostate cancer
- Pruritus (severe itching of the skin)
- Rash generalised (rash on most of body parts)
- Rash pruritic (redness with itching)
- Renal failure (kidney dysfunction)
- Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
- Scrotal irritation (irritation in scrotum)
60+:
- Ankle fracture
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Pneumonia
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Chills (felling of cold)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Erythema (redness of the skin)
- Gait disturbance
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
What are the existing conditions these people have? *
- Gait Disturbance: 7 people, 21.88%
- Erection Problems: 4 people, 12.50%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 9.38%
- Back Pain: 3 people, 9.38%
- Nausea (feeling of having an urge to vomit): 2 people, 6.25%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Tenormin and Tysabri?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tenormin and Tysabri:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tenormin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tysabri:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tenormin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tysabri and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on atenolol and natalizumab (the active ingredients of Tenormin and Tysabri, respectively), and Tenormin and Tysabri (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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