Topamax and Foradil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Foradil (formoterol fumarate). Common drug interactions include localised oedema among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Foradil. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

What is Foradil?

Foradil has active ingredients of formoterol fumarate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 5,956 Foradil users. Check the latest studies of Foradil.

On Jul, 14, 2026

53 people who take Topamax and Foradil together, and have interactions are studied.

What are the common drug interactions of Topamax and Foradil, by gender? *:

female:

Localised oedema (fluid retention in a particular part of the body)
Malaise (a feeling of general discomfort or uneasiness)
Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
Lymphadenopathy (disease or enlargement of lymph nodes)
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Hepatic neoplasm (liver tumour)
Arrhythmia (irregular heartbeat)
Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
Blood cholesterol increased
Arthralgia (joint pain)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

What are the common drug interactions of Topamax and Foradil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Injection site dryness
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Anaphylactic reaction (serious allergic reaction)
Chronic kidney disease
Dyskinesia (abnormality or impairment of voluntary movement)
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Pruritus (severe itching of the skin)
Renal failure (kidney dysfunction)

40-49:

Oedema (fluid collection in tissue)
Oropharyngeal pain
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteochondrosis (a family of orthopaedic diseases of the joint that occur in children and adolescents)
Pruritus (severe itching of the skin)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Swelling face
Syncope (loss of consciousness with an inability to maintain postural tone)
Type 1 diabetes mellitus

50-59:

Arrhythmia (irregular heartbeat)
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Hepatic steatosis (fatty liver disease)
Localised oedema (fluid retention in a particular part of the body)
Lymphadenopathy (disease or enlargement of lymph nodes)
Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
Arthralgia (joint pain)
Blood cholesterol increased
Blood disorder

60+:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Blood pressure decreased
Haemoglobin decreased
Heart rate increased
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Nausea (feeling of having an urge to vomit)
Streptococcal infection
Vertigo
Blood thyroid stimulating hormone decreased

What are the existing conditions these people have? *

Asthma: 22 people, 41.51%
Depression: 16 people, 30.19%
Sleep Disorder: 14 people, 26.42%
Nausea (feeling of having an urge to vomit): 14 people, 26.42%
Muscle Spasms (muscle contraction): 14 people, 26.42%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 14 people, 26.42%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 13 people, 24.53%
Cough: 11 people, 20.75%
Pain: 6 people, 11.32%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 11.32%

* Approximation only. Some reports may have incomplete information.

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