Topamax and Plan b drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Plan b (levonorgestrel). Common drug interactions include menstruation irregular among females.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Plan b. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

What is Plan b?

Plan b has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 38,623 Plan b users. Check the latest studies of Plan b.

On Jul, 14, 2026

51 people who take Topamax and Plan b together, and have interactions are studied.

What are the common drug interactions of Topamax and Plan B, by gender? *:

female:

Menstruation irregular
Vaginal haemorrhage (vaginal bleeding)
Dizziness
Fatigue (feeling of tiredness)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Vomiting
Abdominal distension
Abdominal pain
Abdominal pain upper

male:

n/a

What are the common drug interactions of Topamax and Plan B, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Breast tenderness
Menstruation irregular
Vulvovaginal discomfort

20-29:

Pelvic pain
Menstruation delayed (late menstruation cycle)
Nausea (feeling of having an urge to vomit)
Abdominal discomfort
Breast pain
Hot flush (sudden feelings of heat)
Menstruation irregular
Vaginal haemorrhage (vaginal bleeding)
Breast tenderness
Vomiting

30-39:

Menstruation irregular
Nausea (feeling of having an urge to vomit)
Pelvic pain
Menstruation delayed (late menstruation cycle)
Dysmenorrhoea (painful menstruation)
Fatigue (feeling of tiredness)
Vaginal haemorrhage (vaginal bleeding)
Abdominal distension
Abdominal pain upper
Arthralgia (joint pain)

40-49:

Fungal infection
Menstruation delayed (late menstruation cycle)
Urinary tract infection
Vaginal discharge
Menstruation irregular
Vaginal haemorrhage (vaginal bleeding)
Alopecia (absence of hair from areas of the body)
Drug screen positive

50-59:

Vaginal haemorrhage (vaginal bleeding)
Back pain
Diarrhoea
Dizziness
Dysmenorrhoea (painful menstruation)
Menstruation irregular

60+:

n/a

What are the existing conditions these people have? *

Stress And Anxiety: 12 people, 23.53%
Depression: 6 people, 11.76%
Sleep Disorder: 5 people, 9.80%
Pain: 4 people, 7.84%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.84%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 7.84%
Asthma: 4 people, 7.84%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 5.88%
Hypersensitivity: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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