Tramadol hydrochloride and Casodex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tramadol hydrochloride (tramadol hydrochloride) and Casodex (bicalutamide). Common drug interactions include asthenia among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Tramadol hydrochloride and Casodex. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Tramadol hydrochloride?

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 40,749 Tramadol hydrochloride users. Check the latest studies of Tramadol hydrochloride.

What is Casodex?

Casodex has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 10,725 Casodex users. Check the latest studies of Casodex.

On Jul, 19, 2026

20 people who take Tramadol hydrochloride and Casodex together, and have interactions are studied.

Tramadol hydrochloride and Casodex drug interactions.

What are the common drug interactions of Tramadol Hydrochloride and Casodex, by gender? *:

female:

Asthenia (weakness)
Blood alkaline phosphatase increased
Blood chloride decreased
Blood sodium decreased
Bone disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac murmur (an heart sound in valve abnormality)
Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
Chills (felling of cold)

male:

Vomiting
Anxiety
Impaired healing
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Neck pain
Rib fracture
Spinal column stenosis (narrowing of spinal column)
Spinal osteoarthritis (joint cartilage loss in spine)
Tooth extraction
Asthenia (weakness)

What are the common drug interactions of Tramadol Hydrochloride and Casodex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Asthenia (weakness)
Bone disorder
Chest pain
Decreased interest
Dental caries
Depression
Dysuria (painful or difficult urination)
Erectile dysfunction
Fatigue (feeling of tiredness)

50-59:

Extraskeletal ossification (formation of bone tissue outside of bone tissue)
Gynaecomastia (enlargement of the gland tissue of the male breast)
Hilar lymphadenopathy (disease of the lymph nodes due to infection)
Hyperkalaemia (damage to or disease of the kidney)
Injury
Lung neoplasm (tumour of lung)
Metastases to bone (cancer spreads to bone)
Metastatic neoplasm (spreadable cancer tumour)
Osteonecrosis of jaw (death of bone of jaw)
Prostate cancer metastatic

60+:

Vomiting
Dehydration (dryness resulting from the removal of water)
Activities of daily living impaired
Agitation (state of anxiety or nervous excitement)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anuria (failure of the kidneys to produce urine)
Anxiety
Arrhythmia (irregular heartbeat)
Arteriosclerosis (thickening and hardening of arteries)
Arthropathy

What are the existing conditions these people have? *

Weakness: 7 people, 35.00%
Hypoaesthesia (reduced sense of touch or sensation): 7 people, 35.00%
Prostate Cancer Metastatic: 3 people, 15.00%
Gastric Ulcer (stomach ulcer): 2 people, 10.00%
Toothaches (tooth pain): 1 person, 5.00%
Stress And Anxiety: 1 person, 5.00%
Osteoporosis (bones weak and more likely to break): 1 person, 5.00%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 5.00%
Muscle Spasms (muscle contraction): 1 person, 5.00%
Menopause (end of monthly cycles in women): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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