Trulicity and Divalproex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Divalproex (divalproex sodium). Common drug interactions include dysphagia among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Divalproex. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

On Aug, 05, 2026

58 people who take Trulicity and Divalproex together, and have interactions are studied.

Trulicity and Divalproex drug interactions.

What are the common drug interactions of Trulicity and Divalproex, by gender? *:

female:

Dysphagia (a condition in which swallowing is difficult or painful)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Pneumonia
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Adenovirus infection
Fungal infection
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Abdominal distension
Abdominal pain
Aggression

male:

Headache (pain in head)
Burning sensation
Wheezing (a high-pitched whistling sound made while you breath)
Blood glucose increased
Hallucination (an experience involving the perception of something not present)
Pneumonia
Dry mouth
Arthralgia (joint pain)
Blood pressure increased
Infection

What are the common drug interactions of Trulicity and Divalproex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Acne (skin problems that cause pimples)
Drug hypersensitivity
Essential tremor
Gastrointestinal motility disorder (abnormal intestinal contractions)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Nephrolithiasis (calculi in the kidneys)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Drug ineffective
Surgery

40-49:

Somnolence (a state of near-sleep, a strong desire for sleep)
Adverse drug reaction
Blood glucose decreased
Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
Constipation
Decreased activity
Eating disorder
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Insomnia (sleeplessness)
Intestinal obstruction

50-59:

Pneumonia
Hallucination (an experience involving the perception of something not present)
Blood glucose increased
Bacterial infection
Cholecystitis acute (rapid infection of gallbladder)
Confusional state
Depression
Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Gastrointestinal stromal tumour (a cancer that arises from transformed cells of mesenchymal origin in gastrointestinal tract)
Hallucination, visual (seeing things that aren't there)

60+:

Allergic sinusitis
Blood pressure increased
Sinusitis (inflammation of sinus)
Vertigo positional
Drug hypersensitivity
Laryngitis bacterial (inflammation of the larynx caused by a bacterial infection)
Low density lipoprotein decreased (cholesterol decreased)
Adenovirus infection
Fungal infection
Pharyngitis (inflammation of the pharynx, causing a sore throat)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 29.31%
High Blood Pressure: 10 people, 17.24%
Type 2 Diabetes: 8 people, 13.79%
Immunodeficiency Common Variable: 7 people, 12.07%
Drowsiness: 7 people, 12.07%
Diabetes: 7 people, 12.07%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 12.07%
Parkinson's Disease: 6 people, 10.34%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 6.90%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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