Verapamil hcl and Coreg drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Verapamil hcl (verapamil hydrochloride) and Coreg (carvedilol). Common drug interactions include bladder disorder among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Verapamil hcl and Coreg. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Verapamil hcl?

Verapamil hcl has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,807 Verapamil hcl users. Check the latest studies of Verapamil hcl.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.



On Jul, 12, 2026

17 people who take Verapamil hcl and Coreg together, and have interactions are studied.

Verapamil hcl and Coreg drug interactions.

What are the common drug interactions of Verapamil Hcl and Coreg, by gender? *:

female:

  1. Bladder disorder
  2. Bone disorder
  3. Bone pain
  4. Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cardiac flutter (abnormal heart rhythm)
  7. Carotid bruit (sound heard over the carotid artery area during auscultation)
  8. Cataract (clouding of the lens inside the eye)
  9. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  10. Deafness

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Cardiomegaly (increased size of heart than normal)
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  5. Headache (pain in head)
  6. Hypoxia (low oxygen in tissues)
  7. Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
  8. Oedema (fluid collection in tissue)
  9. Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
  10. Lung disorder (lung disease)

What are the common drug interactions of Verapamil Hcl and Coreg, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Death
  2. Pneumonia

40-49:

  1. Acute respiratory failure
  2. C-reactive protein increased
  3. Hypotension (abnormally low blood pressure)
  4. Lung disorder (lung disease)
  5. Myalgia (muscle pain)
  6. Pyrexia (fever)
  7. Red blood cell sedimentation rate increased
  8. Tinnitus (a ringing in the ears)

50-59:

  1. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  2. Cardiomegaly (increased size of heart than normal)
  3. Cerebral haemorrhage (bleeding within the brain)
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Dyspnoea (difficult or laboured respiration)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  8. Headache (pain in head)
  9. Hypoxia (low oxygen in tissues)
  10. Insomnia (sleeplessness)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pain in jaw
  3. Bladder disorder
  4. Bone disorder
  5. Bone pain
  6. Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Cardiac flutter (abnormal heart rhythm)
  9. Carotid bruit (sound heard over the carotid artery area during auscultation)
  10. Cataract (clouding of the lens inside the eye)

What are the existing conditions these people have? *

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 11.76%
  2. Hyperkalemia (damage to or disease of the kidney): 2 people, 11.76%
  3. Type 2 Diabetes: 1 person, 5.88%
  4. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 1 person, 5.88%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.88%
  6. Breast Cancer Metastatic: 1 person, 5.88%
  7. Cluster Headache (one-sided head pain with tearing): 1 person, 5.88%
  8. Diabetes: 1 person, 5.88%
  9. Dyspnea (difficult or laboured breathing): 1 person, 5.88%
  10. Essential Hypertension (primary hypertension): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Verapamil hcl and Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Verapamil hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Verapamil hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coreg and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride and carvedilol (the active ingredients of Verapamil hcl and Coreg, respectively), and Verapamil hcl and Coreg (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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