Vesicare and Astepro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vesicare (solifenacin succinate) and Astepro (azelastine hydrochloride). Common drug interactions include ankle fracture among females and duodenal ulcer among males.

The phase IV clinical study analyzes what interactions people have when they take Vesicare and Astepro. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,656 Vesicare users. Check the latest studies of Vesicare.

What is Astepro?

Astepro has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 3,336 Astepro users. Check the latest studies of Astepro.

On Jul, 20, 2026

20 people who take Vesicare and Astepro together, and have interactions are studied.

What are the common drug interactions of Vesicare and Astepro, by gender? *:

female:

Ankle fracture
Anxiety
Blepharitis (chronic inflammation of the eyelid)
Breast pain
Cervical vertebral fracture
Chest pain
Cough
Drug ineffective
Emotional distress
Erythema (redness of the skin)

male:

Duodenal ulcer
Inappropriate antidiuretic hormone secretion
Fall
Gastritis (inflammation of stomach)
Hypertension (high blood pressure)
Oesophagitis (inflammation of oesophagus)
Chorioretinopathy (collection of fluid under the retina that results in visual distortion)

What are the common drug interactions of Vesicare and Astepro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Emotional distress
Gallbladder disorder
General physical health deterioration (weak health status)
Injection site reaction
Injury
Jugular vein thrombosis (clot in jugular vein)
Pain
Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)
Wheezing (a high-pitched whistling sound made while you breath)

50-59:

Breast pain
Erythema (redness of the skin)

60+:

Duodenal ulcer
Inappropriate antidiuretic hormone secretion
Injection site pruritus (severe itching at injection site)
Injection site swelling
Oedema peripheral (superficial swelling)
Pelvic fracture
Pneumonia
Pruritus (severe itching of the skin)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Fall

What are the existing conditions these people have? *

Depression: 5 people, 25.00%
Insomnia (sleeplessness): 5 people, 25.00%
Asthma: 4 people, 20.00%
Back Pain: 4 people, 20.00%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 20.00%
Prostate Cancer: 4 people, 20.00%
Urination - Excessive At Night: 4 people, 20.00%
Hypersensitivity: 3 people, 15.00%
Parkinson's Disease: 3 people, 15.00%
Urine Flow Decreased: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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