Vesicare and Creon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vesicare (solifenacin succinate) and Creon (pancrelipase (amylase;lipase;protease)). Common drug interactions include ecchymosis among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Vesicare and Creon. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,655 Vesicare users. Check the latest studies of Vesicare.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

96 people who take Vesicare and Creon together, and have interactions are studied.

What are the common drug interactions of Vesicare and Creon, by gender? *:

female:

Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Hepatic infarction (particular area of the liver has lost its blood supply and died)
Hepatic steatosis (fatty liver disease)
Hepatomegaly (abnormal enlargement of the liver)
Jaundice cholestatic
Liver disorder (liver diseases)
Neck pain
Nocturia (the need to get up in the night to urinate)
Pancreatic carcinoma (pancreatic cancer)
Peripancreatic fluid collection

male:

Diarrhoea
Vomiting
Malaise (a feeling of general discomfort or uneasiness)
Pulmonary mass
Renal cyst (kidney cyst)
Renal disorder (kidney disease)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tobacco abuse
Anaemia (lack of blood)
Back pain

What are the common drug interactions of Vesicare and Creon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

40-49:

Overdose
Acute respiratory failure
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dizziness
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Hepatic infarction (particular area of the liver has lost its blood supply and died)
Hepatic steatosis (fatty liver disease)
Hepatomegaly (abnormal enlargement of the liver)
Liver disorder (liver diseases)
Peripancreatic fluid collection

50-59:

Intestinal polyp (small growths in the bowel with the potential for further growth)
Jaundice cholestatic
Pancreatic carcinoma (pancreatic cancer)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Pulmonary mass
Renal cyst (kidney cyst)
Renal disorder (kidney disease)
Sinus disorder (disease of sinus)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tobacco abuse

60+:

Diarrhoea
Vomiting
Deafness
Ear infection
Ear pain
Flushing (the warm, red condition of human skin)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Loss of consciousness
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 18.75%
Immunodeficiency Common Variable: 16 people, 16.67%
High Blood Pressure: 15 people, 15.62%
Stress And Anxiety: 14 people, 14.58%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 10 people, 10.42%
Fibromyalgia (a long-term condition which causes pain all over the body): 10 people, 10.42%
Insomnia (sleeplessness): 9 people, 9.38%
Depression: 7 people, 7.29%
Back Pain: 7 people, 7.29%
Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 7 people, 7.29%

* Approximation only. Some reports may have incomplete information.

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