Viagra and Medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viagra (sildenafil citrate) and Medrol (methylprednisolone). Common drug interactions include cough among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Viagra and Medrol. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.

What is Medrol?

Medrol has active ingredients of methylprednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 24,443 Medrol users. Check the latest studies of Medrol.

On Jul, 12, 2026

98 people who take Viagra and Medrol together, and have interactions are studied.

What are the common drug interactions of Viagra and Medrol, by gender? *:

female:

Cough
Death
Ear discomfort
Essential hypertension (primary hypertension)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nephrolithiasis (calculi in the kidneys)
Renal colic (renal pain)
Renal failure (kidney dysfunction)
Ureteric stenosis (abnormal narrowing or contraction of a duct or canal)
Urethral pain

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Neuropathy peripheral (surface nerve damage)
Osteopenia (a condition where bone mineral density is lower than normal)
Bone density decreased
Constipation
Gait disturbance
Peroneal nerve palsy
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of Viagra and Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Foot fracture
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety
Bone density decreased
Depression
Emotional distress
Gait disturbance
Hand fracture
Muscle atrophy (a decrease in the mass of the muscle)

30-39:

Blood viscosity increased
Cough
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Muscle spasms (muscle contraction)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

Depression
Dyspnoea (difficult or laboured respiration)
Accident at work
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Back pain
Blindness unilateral
Brain injury
Cerebellar ataxia (loss of coordination)

50-59:

Chest pain
Dizziness
Lung hyperinflation (inspiration of more than normal)
Pupil fixed
Skin discolouration (change of skin colour)
Weight increased
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal pain
Acute myocardial infarction (acute heart attack)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Optic neuropathy (optic nerve damage)
Osteopenia (a condition where bone mineral density is lower than normal)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back pain
Blood creatinine increased

What are the existing conditions these people have? *

Pain: 20 people, 20.41%
High Blood Pressure: 15 people, 15.31%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 14.29%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 11.22%
Hiv Infection: 9 people, 9.18%
High Blood Cholesterol: 9 people, 9.18%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 7.14%
Upper Respiratory Tract Infection: 5 people, 5.10%
Stress And Anxiety: 5 people, 5.10%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 5.10%

* Approximation only. Some reports may have incomplete information.

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