Xtandi and Augmentin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Xtandi (enzalutamide) and Augmentin (amoxicillin; clavulanate potassium). Common drug interactions include fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Xtandi and Augmentin. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Xtandi?
Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.
What is Augmentin?
Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.
34 people who take Xtandi and Augmentin together, and have interactions are studied.

What are the common drug interactions of Xtandi and Augmentin, by gender? *:
female:
n/a
male:
- Fatigue (feeling of tiredness)
- Diarrhoea
- Hyperhidrosis (abnormally increased sweating)
- Malaise (a feeling of general discomfort or uneasiness)
- Nasopharyngitis (inflammation of the nasopharynx)
- Neuropathy peripheral (surface nerve damage)
- Rash
- Visual impairment
- Arthralgia (joint pain)
- Memory impairment
What are the common drug interactions of Xtandi and Augmentin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Fatigue (feeling of tiredness)
- Diarrhoea
- Oedema peripheral (superficial swelling)
- Constipation
- Depression
- Epistaxis (bleed from the nose)
- Headache (pain in head)
- Influenza like illness
- Insomnia (sleeplessness)
- Malignant neoplasm progression (cancer tumour came back)
What are the existing conditions these people have? *
- Prostate Cancer: 23 people, 67.65%
- Metastases To Bone (cancer spreads to bone): 6 people, 17.65%
- Metastases To Bone Marrow (cancer spreads to bone marrow): 4 people, 11.76%
- Wheezing (a high-pitched whistling sound made while you breath): 3 people, 8.82%
- Itching: 3 people, 8.82%
- Otitis (ear infection): 2 people, 5.88%
- Bone Disorder: 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Xtandi and Augmentin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Xtandi and Augmentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Xtandi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Augmentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xtandi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Augmentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on enzalutamide and amoxicillin; clavulanate potassium (the active ingredients of Xtandi and Augmentin, respectively), and Xtandi and Augmentin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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