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Xyrem and Mycelex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xyrem (sodium oxybate) and Mycelex (clotrimazole). Common drug interactions include hospitalisation among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Xyrem and Mycelex. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Xyrem?

Xyrem has active ingredients of sodium oxybate. It is often used in narcolepsy. eHealthMe is studying from 81,487 Xyrem users. Check the latest studies of Xyrem.

What is Mycelex?

Mycelex has active ingredients of clotrimazole. eHealthMe is studying from 1,876 Mycelex users. Check the latest studies of Mycelex.

On Jul, 19, 2026

12 people who take Xyrem and Mycelex together, and have interactions are studied.

Xyrem and Mycelex drug interactions.

What are the common drug interactions of Xyrem and Mycelex, by gender? *:

female:

  1. Hospitalisation
  2. Drug abuse
  3. Blood creatinine decreased
  4. Blood pressure decreased
  5. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  6. Drug hypersensitivity
  7. Fluid retention (an abnormal accumulation of fluid in the blood)
  8. Hypersomnia (excessive daytime sleepiness (eds))
  9. Oral candidiasis (fungal infection of mouth)
  10. Pneumonia

male:

  1. Anxiety
  2. Gait disturbance

What are the common drug interactions of Xyrem and Mycelex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Anxiety
  2. Gait disturbance

60+:

  1. Depression
  2. Suicidal ideation
  3. Oral candidiasis (fungal infection of mouth)
  4. Pneumonia
  5. Pulmonary mass
  6. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  7. Sinusitis (inflammation of sinus)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Surgery
  10. Tobacco abuse

What are the existing conditions these people have? *

  1. Asthma: 2 people, 16.67%
  2. Prostatomegaly (enlargement of the prostate): 1 person, 8.33%
  3. Pain: 1 person, 8.33%
  4. Indigestion: 1 person, 8.33%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 8.33%
  6. Hypersensitivity: 1 person, 8.33%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 8.33%
  9. Dry Mouth: 1 person, 8.33%
  10. Drowsiness: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Xyrem and Mycelex?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xyrem and Mycelex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xyrem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mycelex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xyrem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mycelex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sodium oxybate and clotrimazole (the active ingredients of Xyrem and Mycelex, respectively), and Xyrem and Mycelex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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