Yaz and Dexamethasone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Yaz (drospirenone; ethinyl estradiol) and Dexamethasone (dexamethasone). Common drug interactions include anhedonia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Yaz and Dexamethasone. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

On Jul, 20, 2026

97 people who take Yaz and Dexamethasone together, and have interactions are studied.

Yaz and Dexamethasone drug interactions.

What are the common drug interactions of Yaz and Dexamethasone, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Abdominal pain
Fatigue (feeling of tiredness)
Fear
Dizziness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Abdominal pain upper
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

male:

Pain
Anxiety
Septic shock (shock due to blood infection)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspnoea (difficult or laboured respiration)
Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Asthenia (weakness)
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)

What are the common drug interactions of Yaz and Dexamethasone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pain
Anxiety
Injury
Pulmonary embolism (blockage of the main artery of the lung)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Dizziness
Fear
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gallbladder disorder

20-29:

Pain
Pulmonary embolism (blockage of the main artery of the lung)
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder disorder
Injury
Abdominal pain upper
Splenic infarction (tissue damage of spleen)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Abdominal pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

30-39:

Pulmonary embolism (blockage of the main artery of the lung)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Injury
Anxiety
Headache (pain in head)
Memory impairment
Speech disorder
Aphasia (damage to the parts of the brain that control language)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Emotional distress
Pain
Fatigue (feeling of tiredness)
Anxiety
Injury
Pain in extremity
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder non-functioning

50-59:

Drug ineffective
Drug toxicity
Embolism arterial (blood clot that has travelled through your arteries and become stuck)
Iatrogenic injury (iatrogenic injury is a form of medical error)
Renal failure chronic (long lasting kidney dysfunction)
Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)
Abdominal pain
Anal fistula
Anxiety
Asthenia (weakness)

60+:

Pain
Anxiety
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Asthenia (weakness)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea

What are the existing conditions these people have? *

Pain: 21 people, 21.65%
Acne (skin problems that cause pimples): 16 people, 16.49%
Stress And Anxiety: 14 people, 14.43%
Premenstrual Syndrome: 12 people, 12.37%
Nausea (feeling of having an urge to vomit): 7 people, 7.22%
Depression: 7 people, 7.22%
Diabetes: 6 people, 6.19%
Migraine (headache): 5 people, 5.15%
Menstruation Irregular: 5 people, 5.15%
High Blood Cholesterol: 5 people, 5.15%

* Approximation only. Some reports may have incomplete information.

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