Zanaflex and Maxipime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zanaflex (tizanidine hydrochloride) and Maxipime (cefepime hydrochloride). Common drug interactions include loss of consciousness among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Zanaflex and Maxipime. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,476 Zanaflex users. Check the latest studies of Zanaflex.

What is Maxipime?

Maxipime has active ingredients of cefepime hydrochloride. eHealthMe is studying from 4,279 Maxipime users. Check the latest studies of Maxipime.

On Aug, 02, 2026

19 people who take Zanaflex and Maxipime together, and have interactions are studied.

Zanaflex and Maxipime drug interactions.

What are the common drug interactions of Zanaflex and Maxipime, by gender? *:

female:

Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Myalgia (muscle pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pain in extremity
Psychotic disorder
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Pneumonia
Anxiety
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Light chain analysis increased
Myelitis transverse (a neurological condition consisting of an inflammatory process of the spinal cord)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Osteoporosis (bones weak and more likely to break)

What are the common drug interactions of Zanaflex and Maxipime, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Acute hepatic failure
Arthralgia (joint pain)
Aspartate aminotransferase increased
Decreased appetite
Encephalopathy (functioning of the brain is affected by some agent or condition)
Epistaxis (bleed from the nose)
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypercalcaemia (elevated calcium (ca+) level in the blood)

30-39:

n/a

40-49:

Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic calcification (aortic calcification sign of heart valve disease)
Aortic valve incompetence
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthropathy
Asthenia (weakness)
Balance disorder
Beta 2 microglobulin increased
Bone cyst

50-59:

Exostosis (formation of new bone on the surface of a bone)
Failure to thrive (inadequate weight gain and physical growth in children)
Haematochezia (passage of stools containing blood)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Light chain analysis increased
Myelitis transverse (a neurological condition consisting of an inflammatory process of the spinal cord)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)

60+:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 52.63%
Back Pain: 6 people, 31.58%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 5 people, 26.32%
Nausea (feeling of having an urge to vomit): 3 people, 15.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.79%
Pain: 2 people, 10.53%
Pneumonia: 2 people, 10.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 10.53%
Cardiac Disorder: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Zanaflex and Maxipime?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously