Zelnorm and Erythromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zelnorm (tegaserod maleate) and Erythromycin (erythromycin). Common drug interactions include gastrooesophageal reflux disease among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Zelnorm and Erythromycin. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

What is Erythromycin?

Erythromycin has active ingredients of erythromycin. It is often used in acne. eHealthMe is studying from 12,563 Erythromycin users. Check the latest studies of Erythromycin.

On Jul, 15, 2026

34 people who take Zelnorm and Erythromycin together, and have interactions are studied.

Zelnorm and Erythromycin drug interactions.

What are the common drug interactions of Zelnorm and Erythromycin, by gender? *:

female:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypotension (abnormally low blood pressure)
Vomiting
Decreased appetite
Device related infection
Dysphagia (a condition in which swallowing is difficult or painful)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Injury
Muscular weakness (muscle weakness)
Pneumonia

male:

Depression
Emotional distress
Impaired gastric emptying
Injury
Lung neoplasm malignant (cancer tumour of lung)
Mouth ulceration (mouth ulcers)
Neuropathy peripheral (surface nerve damage)
Obstruction gastric (obstruction in stomach)
Oesophagitis ulcerative (inflammation of oesophagus with multiple ulcers)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

What are the common drug interactions of Zelnorm and Erythromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Device related infection
Disease progression
Intestinal perforation (complete penetration of the wall of the intestine)
Intestinal resection
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

20-29:

Abdominal pain
Acute abdomen
Ileus (a painful obstruction of the ileum or other part of the intestine)
Intestinal gangrene
Ovarian cyst ruptured (tear in fluid filled sac of the ovary)
Pulmonary embolism (blockage of the main artery of the lung)
Vomiting

30-39:

General physical health deterioration (weak health status)
Abdominal pain
Anaemia (lack of blood)
Bacteraemia (presence of bacteria in the blood)
Calculus urinary (stone in urinary system)
Cardiomyopathy (weakening of the heart muscle)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Emotional disorder
Mitral valve disease (disease of mitral valve of heart)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

40-49:

Blood glucose increased
Cough
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Glossodynia (a burning or painful sensation in the tongue)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pyrexia (fever)

50-59:

Foot fracture
Helicobacter test positive
Hypoxia (low oxygen in tissues)
Intervertebral disc protrusion (spinal disc protrusion)
Lymphatic system neoplasm (tumour of lymphatic system)
Lymphoma (cancer that begins in immune system cells)
Malaise (a feeling of general discomfort or uneasiness)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Neutropenia (an abnormally low number of neutrophils)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute left ventricular failure (heart attack)
Chest pain
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Chronic kidney disease
Clavicle fracture
Colonic polyp (extra part of colon tissue grow in intestine)
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea

What are the existing conditions these people have? *

Impaired Gastric Emptying: 7 people, 20.59%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 20.59%
High Blood Pressure: 7 people, 20.59%
Nausea (feeling of having an urge to vomit): 6 people, 17.65%
Headache (pain in head): 5 people, 14.71%
Hypersensitivity: 4 people, 11.76%
Cardiac Disorder: 4 people, 11.76%
Diabetes: 4 people, 11.76%
Depression: 4 people, 11.76%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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