Zetia and Actiq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zetia (ezetimibe) and Actiq (fentanyl citrate). Common drug interactions include sinusitis among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Zetia and Actiq. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.

What is Actiq?

Actiq has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 27,583 Actiq users. Check the latest studies of Actiq.

On Jul, 10, 2026

16 people who take Zetia and Actiq together, and have interactions are studied.

What are the common drug interactions of Zetia and Actiq, by gender? *:

female:

Sinusitis (inflammation of sinus)
Abscess oral (abscess in the mouth)
Anaemia (lack of blood)
Arteriosclerosis (thickening and hardening of arteries)
Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
Bone disorder
Bone fistula
Cardiac failure congestive
Carotid artery stenosis (narrowing of carotid artery)
Cellulitis (infection under the skin)

male:

Drug ineffective
Fall
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Ligament sprain (ligament stretched)
Breakthrough pain
Chest pain
Drug effect decreased

What are the common drug interactions of Zetia and Actiq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

40-49:

Application site ulcer
Muscle spasms (muscle contraction)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Injection site pain
Malaise (a feeling of general discomfort or uneasiness)
Mouth ulceration (mouth ulcers)
Neoplasm (tumour)
Oropharyngeal blistering (blister of oropharynx)
Pyrexia (fever)

60+:

Fall
Abscess oral (abscess in the mouth)
Cerebral atrophy (decrement in size of brain)
Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
Colostomy
Contusion (a type of hematoma of tissue in which capillaries)
Deafness
Depression
Device failure
Diarrhoea

What are the existing conditions these people have? *

Asthma: 5 people, 31.25%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 25.00%
High Blood Pressure: 3 people, 18.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
Stress And Anxiety: 2 people, 12.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
Panic Disorder: 2 people, 12.50%
Neuralgia (pain in one or more nerves): 2 people, 12.50%
Back Pain: 2 people, 12.50%
Insomnia (sleeplessness): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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