Zide and Uceris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zide (hydrochlorothiazide) and Uceris (budesonide). Common drug interactions include anxiety among females and haemorrhoids among males.

The phase IV clinical study analyzes what interactions people have when they take Zide and Uceris. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Zide?

Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,246 Zide users. Check the latest studies of Zide.

What is Uceris?

Uceris has active ingredients of budesonide. It is often used in ulcerative colitis. eHealthMe is studying from 1,721 Uceris users. Check the latest studies of Uceris.

On Jul, 16, 2026

20 people who take Zide and Uceris together, and have interactions are studied.

What are the common drug interactions of Zide and Uceris, by gender? *:

female:

Anxiety
Abdominal pain upper
Precancerous skin lesion
Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
Volvulus (obstruction caused by twisting of the stomach or intestine)
Arthralgia (joint pain)
Blood cholesterol increased
Dyspnoea (difficult or laboured respiration)
Fall
Femoral hernia (a bulging located near the groin and thigh that occurs when a small part of intestine pushes through the wall of the femoral artery)

male:

Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Urinary tract infection
Hepatitis (inflammation of the liver)
Intestinal obstruction
Large intestinal haemorrhage (bleeding in large intestine)
Procedural pain
Prostatomegaly (enlargement of the prostate)
Rectal haemorrhage (bleeding from anus)
Small intestinal obstruction (blockage in small intestine)
Vitamin d deficiency

What are the common drug interactions of Zide and Uceris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Vitamin d deficiency
Intervertebral disc protrusion (spinal disc protrusion)
Intestinal obstruction
Procedural pain
Small intestinal obstruction (blockage in small intestine)

50-59:

Urinary tract infection
Abdominal pain
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic enzyme increased
Hepatitis (inflammation of the liver)
Prostatomegaly (enlargement of the prostate)

60+:

Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Abdominal pain upper
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Burning sensation
Cough
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Erythema (redness of the skin)
Feeling hot
Infection
Injection site mass

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 30.00%
Thyroid Diseases: 2 people, 10.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 10.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 10.00%
Colitis Microscopic (inflammation of colon with diarrhoea and abdominal cramps): 2 people, 10.00%
Drowsiness: 2 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.00%
Hypersensitivity: 2 people, 10.00%
High Blood Cholesterol: 2 people, 10.00%
Pain: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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