Esgic-plus and Diazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Esgic-plus (acetaminophen; butalbital; caffeine) and Diazepam (diazepam). Common drug interactions include fall among females.

The phase IV clinical study analyzes what interactions people have when they take Esgic-plus and Diazepam. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Esgic-plus?

Esgic-plus has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 269 Esgic-plus users. Check the latest studies of Esgic-plus.

What is Diazepam?

Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.

On Jul, 16, 2026

11 people who take Esgic-plus and Diazepam together, and have interactions are studied.

Esgic-plus and Diazepam drug interactions.

What are the common drug interactions of Esgic-Plus and Diazepam, by gender? *:

female:

Fall
Mydriasis (a dilation of the pupil)
Sternal fracture
Ventricular fibrillation (abnormally irregular heart rhythm)
Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Apnoea (suspension of external breathing)
Bladder neck suspension
Body temperature decreased
Bradycardia (abnormally slow heart action)

male:

n/a

What are the common drug interactions of Esgic-Plus and Diazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arrhythmia (irregular heartbeat)
Cardiac arrest
Coma (state of unconsciousness lasting more than six hours)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Depressed level of consciousness
Fall
Influenza like illness
Mydriasis (a dilation of the pupil)
Nephrosclerosis (hardening of the kidney due to renovascular disease)
Pulse absent

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Neuromyopathy (disease of both muscles and nerves)
Osteoporosis (bones weak and more likely to break)
Otitis media (inflammation of the middle ear)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Sinusitis (inflammation of sinus)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Visual impairment
Agitation (state of anxiety or nervous excitement)

60+:

Eye pain
Mydriasis (a dilation of the pupil)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 63.64%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 63.64%

* Approximation only. Some reports may have incomplete information.

Do you take Esgic-plus and Diazepam?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously