Zoloft and Injectafer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Injectafer (ferric carboxymaltose). Common drug interactions include malaise among females.

The phase IV clinical study analyzes what interactions people have when they take Zoloft and Injectafer. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Injectafer?

Injectafer has active ingredients of ferric carboxymaltose. eHealthMe is studying from 3,270 Injectafer users. Check the latest studies of Injectafer.



On Jul, 26, 2026

12 people who take Zoloft and Injectafer together, and have interactions are studied.

Zoloft and Injectafer drug interactions.

What are the common drug interactions of Zoloft and Injectafer, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  3. Muscle twitching
  4. Nausea (feeling of having an urge to vomit)
  5. Pain
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Rash
  8. Vision blurred
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Chills (felling of cold)

male:

n/a

What are the common drug interactions of Zoloft and Injectafer, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Headache (pain in head)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Chills (felling of cold)
  4. Emotional distress
  5. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Pain
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  9. Vision blurred
  10. Maternal exposure during pregnancy (use of substance during pregnancy)

30-39:

  1. Balance disorder
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Dizziness
  4. Fall
  5. Foot fracture
  6. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Onychomadesis (a periodic idiopathic shedding of the nails)

40-49:

  1. Abdominal pain upper
  2. Cough
  3. Decreased appetite
  4. Dizziness
  5. Heart rate increased
  6. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
  7. Pain
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Vaginal haemorrhage (vaginal bleeding)
  10. Vision blurred

50-59:

  1. Anaphylactic reaction (serious allergic reaction)

60+:

  1. Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)

What are the existing conditions these people have? *

  1. Iron Deficiency Anaemia: 8 people, 66.67%
  2. Anaemia (lack of blood): 4 people, 33.33%
  3. Pain: 3 people, 25.00%
  4. Stress And Anxiety: 2 people, 16.67%
  5. Serum Ferritin Decreased: 2 people, 16.67%
  6. Vitamin B12 Deficiency: 2 people, 16.67%
  7. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 2 people, 16.67%
  8. Heavy Or Prolong Menstrual Bleeding: 2 people, 16.67%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 8.33%
  10. Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zoloft and Injectafer:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Injectafer:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoloft and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Injectafer and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride and ferric carboxymaltose (the active ingredients of Zoloft and Injectafer, respectively), and Zoloft and Injectafer (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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