Zoloft and Voriconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Voriconazole (voriconazole). Common drug interactions include tremor among females and acute lymphocytic leukaemia recurrent among males.

The phase IV clinical study analyzes what interactions people have when they take Zoloft and Voriconazole. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Voriconazole?

Voriconazole has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 21,706 Voriconazole users. Check the latest studies of Voriconazole.

On Aug, 04, 2026

81 people who take Zoloft and Voriconazole together, and have interactions are studied.

Zoloft and Voriconazole drug interactions.

What are the common drug interactions of Zoloft and Voriconazole, by gender? *:

female:

Tremor (trembling or shaking movements in one or more parts of your body)
Asthenia (weakness)
Confusional state
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Photophobia (extreme sensitivity to light)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Headache (pain in head)
Balance disorder

male:

Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Blood glucose increased
Blood immunoglobulin g decreased
Blood lactate dehydrogenase increased
Blood phosphorus decreased
Blood potassium decreased
Blood sodium decreased
Blood triglycerides increased
C-reactive protein increased

What are the common drug interactions of Zoloft and Voriconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Febrile neutropenia (fever with reduced white blood cells)

10-19:

Pyrexia (fever)
Mydriasis (a dilation of the pupil)
Headache (pain in head)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Confusional state
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Fatigue (feeling of tiredness)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)

20-29:

Pulmonary embolism (blockage of the main artery of the lung)
Respiratory distress (difficulty in breathing)
Hodgkin's disease (cancer originating from white blood cells)
Loss of consciousness
Pneumonia
Unresponsive to stimuli

30-39:

Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Disease progression
Neutropenia (an abnormally low number of neutrophils)
Pneumococcal infection (infection caused by streptococcus pneumoniae)
Streptococcal infection

40-49:

Asthenia (weakness)
Death
Depressed level of consciousness
Leukaemia recurrent (repeat cancer of bone marrow or blood cells)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Hypokalaemia (low potassium)
Abdominal pain
Arteriovenous fistula site complication
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Colitis (inflammation of colon)

50-59:

Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Lung disorder (lung disease)
Bradycardia (abnormally slow heart action)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dehydration (dryness resulting from the removal of water)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Infection
Muscular weakness (muscle weakness)

60+:

Febrile neutropenia (fever with reduced white blood cells)
Gastroenteritis staphylococcal (inflammation of stomach and intestine caused by staphylococcal infection)
Bilirubin conjugated increased
Blood creatinine increased
Blood glucose decreased
Blood glucose increased
Blood pressure systolic increased
Bone density decreased
Culture urine positive
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Pain: 24 people, 29.63%
Nausea (feeling of having an urge to vomit): 19 people, 23.46%
Nausea And Vomiting: 16 people, 19.75%
B-Cell Type Acute Leukaemia (cancer of the white blood cells): 13 people, 16.05%
Fever: 12 people, 14.81%
Constipation: 12 people, 14.81%
Hodgkin's Lymphoma (cancer originating from white blood cells): 8 people, 9.88%
Stress And Anxiety: 7 people, 8.64%
Sleep Disorder: 7 people, 8.64%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 8.64%

* Approximation only. Some reports may have incomplete information.

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