Zyrtec and Carbatrol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Carbatrol (carbamazepine). Common drug interactions include blood cholesterol increased among females and convulsion among males.
The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Carbatrol. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Zyrtec?
Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.
What is Carbatrol?
Carbatrol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 1,979 Carbatrol users. Check the latest studies of Carbatrol.
26 people who take Zyrtec and Carbatrol together, and have interactions are studied.

What are the common drug interactions of Zyrtec and Carbatrol, by gender? *:
female:
- Blood cholesterol increased
- Diarrhoea
- Bacterial test positive
- Fibroma (tumours that are composed of fibrous or connective tissue)
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Respiratory tract infection
- Urine abnormality
- Vomiting
- White blood cells urine positive
- Acne (skin problems that cause pimples)
male:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Blood calcium decreased
- Dyspnoea (difficult or laboured respiration)
- Haematocrit decreased
- Haemoglobin decreased
- Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Oral intake reduced
- Pain
What are the common drug interactions of Zyrtec and Carbatrol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Asthenia (weakness)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Bilirubin conjugated increased
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Eosinophil percentage increased
10-19:
n/a
20-29:
- Abnormal behaviour
- Aggression
- Asthenia (weakness)
- Dyskinesia (abnormality or impairment of voluntary movement)
- Gingival bleeding (bleeding gums)
- Gingivitis (inflammation of gums)
- Hypotension (abnormally low blood pressure)
- Ligament rupture (tear in ligament)
- Mouth ulceration (mouth ulcers)
- Platelet count decreased
30-39:
- Blood cholesterol increased
- Bacterial test positive
- Diarrhoea
- Fibroma (tumours that are composed of fibrous or connective tissue)
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Respiratory tract infection
- Urine abnormality
- Vomiting
- White blood cells urine positive
- Acne (skin problems that cause pimples)
40-49:
- Contusion (a type of hematoma of tissue in which capillaries)
- Nail discolouration (change in nail colour)
- Nodule (a growth of abnormal tissue)
- Pain
- Ankle fracture
- Osteoporosis (bones weak and more likely to break)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
50-59:
- Dyspnoea (difficult or laboured respiration)
- Productive cough
- Impulsive behaviour
- Obesity (having too much body fat)
- Pain
- Pneumonia
- Red blood cell count decreased
- Type 2 diabetes mellitus
- Weight increased
- White blood cell count decreased
60+:
n/a
What are the existing conditions these people have? *
- Angiomyolipoma (most common benign tumour of the kidney): 6 people, 23.08%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 11.54%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.69%
- Psoriasis (immune-mediated disease that affects the skin): 2 people, 7.69%
- Hypersensitivity: 2 people, 7.69%
- Asthma: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Zyrtec and Carbatrol?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Zyrtec and Carbatrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zyrtec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Carbatrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zyrtec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Carbatrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
- Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cetirizine hydrochloride and carbamazepine (the active ingredients of Zyrtec and Carbatrol, respectively), and Zyrtec and Carbatrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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