A study for a 65 year old woman who takes Famotidine, Mounjaro, Metformin, Chlorthalidone (an AI-powered real world drug study)
Summary:
21 females aged 65 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 65 year old female patient who has Reflux, Diabetes, High Blood Pressure. The study is created by eHealthMe based on reports from sources including the FDA.
21 females aged 65 (±5) who take Famotidine, Mounjaro, Metformin, Chlorthalidone and have adverse effects are studied.
Number of reports submitted per year:

Information of the patient in this study:
- Age: 65
- Gender: female
What are the drugs?
- Famotidine has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 83,423 Famotidine users. Check the latest studies of Famotidine.
- Mounjaro has active ingredients of tirzepatide. It is often used in weight loss. eHealthMe is studying from 37,669 Mounjaro users. Check the latest studies of Mounjaro.
- Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,355 Metformin users. Check the latest studies of Metformin.
- Chlorthalidone has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 12,482 Chlorthalidone users. Check the latest studies of Chlorthalidone.
What are the conditions?
- Reflux (stomach contents come back up into the food pipe (gullet or oesophagus) or even into the mouth) is found to be associated with 2,545 drugs and 3,481 conditions by eHealthMe. Check the latest studies of Reflux.
- Diabetes is found to be associated with 2,010 drugs and 2,858 conditions by eHealthMe. Check the latest studies of Diabetes.
- High blood pressure is found to be associated with 3,482 drugs and 5,247 conditions by eHealthMe. Check the latest studies of High blood pressure.
What are the adverse effects?
- Low back pain is found to be associated with 27 drugs and 186 conditions by eHealthMe. Check the latest studies of Low back pain.
- Pain - knee is found to be associated with 23 conditions by eHealthMe. Check the latest studies of Pain - knee.
- Joint pain is found to be associated with 3,328 drugs and 5,212 conditions by eHealthMe. Check the latest studies of Joint pain.
- Abnormal dreams is found to be associated with 1,091 drugs and 1,261 conditions by eHealthMe. Check the latest studies of Abnormal dreams.
- Fatigue (feeling of tiredness) is found to be associated with 4,027 drugs and 6,382 conditions by eHealthMe. Check the latest studies of Fatigue.
- Ankle pain is found to be associated with 2 conditions by eHealthMe. Check the latest studies of Ankle pain.
Comparison with patient's specific adverse outcomes:
You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.
By the same drug(s):
-
Low Back Pain:
- among females aged 65 (±5) who take the same drugs: 0% (0 of 21)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 106) -
Pain - Knee:
- among females aged 65 (±5) who take the same drugs: 0% (0 of 21)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 106) -
Joint Pain:
- among females aged 65 (±5) who take the same drugs: 0% (0 of 21)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 106) -
Abnormal Dreams:
- among females aged 65 (±5) who take the same drugs: 0% (0 of 21)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 106) -
Fatigue (feeling of tiredness):
- among females aged 65 (±5) who take the same drugs: 4.76% (1 of 21)
- among people who take the same drugs, regardless of gender or age: 0.94% (1 of 106) -
Ankle Pain:
- among females aged 65 (±5) who take the same drugs: 0% (0 of 21)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 106)
By each condition:
-
people who have Abnormal Dreams with Reflux:
- among females aged 65 (±5) who have Reflux: 0.12% (44 of 36,081)
- among people who have Reflux, regardless of gender or age: 0.1% (345 of 328,777) -
people who have Abnormal Dreams with Diabetes:
- among females aged 65 (±5) who have Diabetes: 0.12% (46 of 37,609)
- among people who have Diabetes, regardless of gender or age: 0.11% (400 of 367,724) -
people who have Abnormal Dreams with High Blood Pressure:
- among females aged 65 (±5) who have High Blood Pressure: 0.3% (230 of 77,577)
- among people who have High Blood Pressure, regardless of gender or age: 0.2% (1,207 of 605,312) -
people who have Ankle Pain with Reflux:
- among females aged 65 (±5) who have Reflux: 0% (0 of 36,081)
- among people who have Reflux, regardless of gender or age: 0% (0 of 328,777) -
people who have Ankle Pain with Diabetes:
- among females aged 65 (±5) who have Diabetes: 0% (0 of 37,609)
- among people who have Diabetes, regardless of gender or age: 0% (0 of 367,724) -
people who have Ankle Pain with High Blood Pressure:
- among females aged 65 (±5) who have High Blood Pressure: 0% (0 of 77,577)
- among people who have High Blood Pressure, regardless of gender or age: 0% (0 of 605,312) -
people who have Fatigue with Diabetes:
- among females aged 65 (±5) who have Diabetes: 4.51% (1,697 of 37,609)
- among people who have Diabetes, regardless of gender or age: 2.94% (10,810 of 367,724) -
people who have Fatigue with High Blood Pressure:
- among females aged 65 (±5) who have High Blood Pressure: 6.2% (4,809 of 77,577)
- among people who have High Blood Pressure, regardless of gender or age: 5.06% (30,608 of 605,312) -
people who have Fatigue with Reflux:
- among females aged 65 (±5) who have Reflux: 3.87% (1,395 of 36,081)
- among people who have Reflux, regardless of gender or age: 2.66% (8,750 of 328,777) -
people who have Joint Pain with Diabetes:
- among females aged 65 (±5) who have Diabetes: 2.91% (1,095 of 37,609)
- among people who have Diabetes, regardless of gender or age: 1.63% (5,978 of 367,724) -
people who have Joint Pain with Reflux:
- among females aged 65 (±5) who have Reflux: 2.73% (985 of 36,081)
- among people who have Reflux, regardless of gender or age: 1.69% (5,561 of 328,777) -
people who have Joint Pain with High Blood Pressure:
- among females aged 65 (±5) who have High Blood Pressure: 4.02% (3,119 of 77,577)
- among people who have High Blood Pressure, regardless of gender or age: 2.95% (17,869 of 605,312) -
people who have Low Back Pain with Reflux:
- among females aged 65 (±5) who have Reflux: 0% (0 of 36,081)
- among people who have Reflux, regardless of gender or age: 0% (0 of 328,777) -
people who have Low Back Pain with Diabetes:
- among females aged 65 (±5) who have Diabetes: 0% (0 of 37,609)
- among people who have Diabetes, regardless of gender or age: 0% (0 of 367,724) -
people who have Low Back Pain with High Blood Pressure:
- among females aged 65 (±5) who have High Blood Pressure: 0% (0 of 77,577)
- among people who have High Blood Pressure, regardless of gender or age: 0% (0 of 605,312) -
people who have Pain - Knee with Diabetes:
- among females aged 65 (±5) who have Diabetes: 0% (0 of 37,609)
- among people who have Diabetes, regardless of gender or age: 0% (0 of 367,724) -
people who have Pain - Knee with Reflux:
- among females aged 65 (±5) who have Reflux: 0% (0 of 36,081)
- among people who have Reflux, regardless of gender or age: 0% (0 of 328,777) -
people who have Pain - Knee with High Blood Pressure:
- among females aged 65 (±5) who have High Blood Pressure: 0% (0 of 77,577)
- among people who have High Blood Pressure, regardless of gender or age: 0% (0 of 605,312)
By each drug (FDA data only):
-
people who take Famotidine and have Abnormal Dreams:
- among females aged 65 (±5) who take Famotidine and have side effects: 0.03% (3 of 9,188)
- among people who take Famotidine and have side effects, regardless of gender or age: 0.08% (64 of 81,933) -
people who take Mounjaro and have Abnormal Dreams:
- among females aged 65 (±5) who take Mounjaro and have side effects: 0.11% (3 of 2,652)
- among people who take Mounjaro and have side effects, regardless of gender or age: 0.06% (21 of 37,587) -
people who take Metformin and have Abnormal Dreams:
- among females aged 65 (±5) who take Metformin and have side effects: 0.14% (80 of 57,078)
- among people who take Metformin and have side effects, regardless of gender or age: 0.16% (716 of 453,942) -
people who take Chlorthalidone and have Abnormal Dreams:
- among females aged 65 (±5) who take Chlorthalidone and have side effects: 0.38% (6 of 1,576)
- among people who take Chlorthalidone and have side effects, regardless of gender or age: 0.16% (19 of 11,959) -
people who take Chlorthalidone and have Ankle Pain:
- among females aged 65 (±5) who take Chlorthalidone and have side effects: 0% (0 of 1,576)
- among people who take Chlorthalidone and have side effects, regardless of gender or age: 0% (0 of 11,959) -
people who take Metformin and have Ankle Pain:
- among females aged 65 (±5) who take Metformin and have side effects: 0% (0 of 57,078)
- among people who take Metformin and have side effects, regardless of gender or age: 0% (0 of 453,942) -
people who take Mounjaro and have Ankle Pain:
- among females aged 65 (±5) who take Mounjaro and have side effects: 0% (0 of 2,652)
- among people who take Mounjaro and have side effects, regardless of gender or age: 0% (0 of 37,587) -
people who take Famotidine and have Ankle Pain:
- among females aged 65 (±5) who take Famotidine and have side effects: 0% (0 of 9,188)
- among people who take Famotidine and have side effects, regardless of gender or age: 0% (0 of 81,933) -
people who take Chlorthalidone and have Fatigue:
- among females aged 65 (±5) who take Chlorthalidone and have side effects: 9.14% (144 of 1,576)
- among people who take Chlorthalidone and have side effects, regardless of gender or age: 8.53% (1,020 of 11,959) -
people who take Famotidine and have Fatigue:
- among females aged 65 (±5) who take Famotidine and have side effects: 6.67% (613 of 9,188)
- among people who take Famotidine and have side effects, regardless of gender or age: 6% (4,913 of 81,933) -
people who take Mounjaro and have Fatigue:
- among females aged 65 (±5) who take Mounjaro and have side effects: 2.04% (54 of 2,652)
- among people who take Mounjaro and have side effects, regardless of gender or age: 2.13% (801 of 37,587) -
people who take Metformin and have Fatigue:
- among females aged 65 (±5) who take Metformin and have side effects: 7.17% (4,091 of 57,078)
- among people who take Metformin and have side effects, regardless of gender or age: 5.82% (26,430 of 453,942) -
people who take Mounjaro and have Joint Pain:
- among females aged 65 (±5) who take Mounjaro and have side effects: 0.64% (17 of 2,652)
- among people who take Mounjaro and have side effects, regardless of gender or age: 0.49% (185 of 37,587) -
people who take Famotidine and have Joint Pain:
- among females aged 65 (±5) who take Famotidine and have side effects: 3.66% (336 of 9,188)
- among people who take Famotidine and have side effects, regardless of gender or age: 2.81% (2,304 of 81,933) -
people who take Chlorthalidone and have Joint Pain:
- among females aged 65 (±5) who take Chlorthalidone and have side effects: 6.41% (101 of 1,576)
- among people who take Chlorthalidone and have side effects, regardless of gender or age: 4.52% (540 of 11,959) -
people who take Metformin and have Joint Pain:
- among females aged 65 (±5) who take Metformin and have side effects: 4.03% (2,301 of 57,078)
- among people who take Metformin and have side effects, regardless of gender or age: 2.85% (12,918 of 453,942) -
people who take Mounjaro and have Low Back Pain:
- among females aged 65 (±5) who take Mounjaro and have side effects: 0% (0 of 2,652)
- among people who take Mounjaro and have side effects, regardless of gender or age: 0% (0 of 37,587) -
people who take Chlorthalidone and have Low Back Pain:
- among females aged 65 (±5) who take Chlorthalidone and have side effects: 0% (0 of 1,576)
- among people who take Chlorthalidone and have side effects, regardless of gender or age: 0% (0 of 11,959) -
people who take Metformin and have Low Back Pain:
- among females aged 65 (±5) who take Metformin and have side effects: 0% (0 of 57,078)
- among people who take Metformin and have side effects, regardless of gender or age: 0% (0 of 453,942) -
people who take Famotidine and have Low Back Pain:
- among females aged 65 (±5) who take Famotidine and have side effects: 0% (0 of 9,188)
- among people who take Famotidine and have side effects, regardless of gender or age: 0% (0 of 81,933) -
people who take Famotidine and have Pain - Knee:
- among females aged 65 (±5) who take Famotidine and have side effects: 0% (0 of 9,188)
- among people who take Famotidine and have side effects, regardless of gender or age: 0% (0 of 81,933) -
people who take Mounjaro and have Pain - Knee:
- among females aged 65 (±5) who take Mounjaro and have side effects: 0% (0 of 2,652)
- among people who take Mounjaro and have side effects, regardless of gender or age: 0% (0 of 37,587) -
people who take Metformin and have Pain - Knee:
- among females aged 65 (±5) who take Metformin and have side effects: 0% (0 of 57,078)
- among people who take Metformin and have side effects, regardless of gender or age: 0% (0 of 453,942) -
people who take Chlorthalidone and have Pain - Knee:
- among females aged 65 (±5) who take Chlorthalidone and have side effects: 0% (0 of 1,576)
- among people who take Chlorthalidone and have side effects, regardless of gender or age: 0% (0 of 11,959)
Common drug interactions *:
- Chronic Kidney Disease : 5 people, 23.81%
- Acute Kidney Failure : 4 people, 19.05%
- Pneumonia : 3 people, 14.29%
- Breast Lump (localized swelling that feels different from the surrounding breast tissue): 2 people, 9.52%
- Cough : 2 people, 9.52%
- Nasopharyngitis (inflammation of the nasopharynx): 2 people, 9.52%
- Cataract (clouding of the lens inside the eye): 2 people, 9.52%
- Upper Respiratory Tract Infection : 2 people, 9.52%
- Atherosclerosis (disorder of the arteries): 1 person, 4.76%
- Cyst (a closed sac): 1 person, 4.76%
- Fungal Infection : 1 person, 4.76%
- Fever : 1 person, 4.76%
- Feeling Hot : 1 person, 4.76%
- Fatigue (feeling of tiredness): 1 person, 4.76%
- Fainting (loss of consciousness and postural tone): 1 person, 4.76%
- Dizziness : 1 person, 4.76%
- Disease Recurrence : 1 person, 4.76%
- Diarrhea : 1 person, 4.76%
- Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 1 person, 4.76%
- Arrhythmias (irregular heartbeat): 1 person, 4.76%
Common co-existing conditions *:
You may use this to check any potential undetected conditions.
- High Blood Cholesterol : 4 people, 19.05%
- Infection : 4 people, 19.05%
- Depression : 3 people, 14.29%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 14.29%
- Pain : 3 people, 14.29%
- Eye Disorder : 3 people, 14.29%
- Nausea (feeling of having an urge to vomit): 3 people, 14.29%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 9.52%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 9.52%
- Neuralgia (pain in one or more nerves): 2 people, 9.52%
- Memory Loss : 2 people, 9.52%
- Menopause (end of monthly cycles in women): 2 people, 9.52%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 9.52%
- Lower Limb Fracture : 2 people, 9.52%
- Itching : 2 people, 9.52%
- Hair Disorder : 2 people, 9.52%
- Inflammation : 2 people, 9.52%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 9.52%
- Constipation : 2 people, 9.52%
- Insomnia (sleeplessness): 2 people, 9.52%
Common co-used drugs *:
You may use this to check any potential interacting drugs.
- Vitamin D3 (6 people, 28.57%)
- Aspirin (6 people, 28.57%)
- Nexium (4 people, 19.05%)
- Protonix (4 people, 19.05%)
- Prilosec (4 people, 19.05%)
- Prevacid (4 people, 19.05%)
- Plavix (3 people, 14.29%)
- Melatonin (3 people, 14.29%)
- Prilosec Otc (3 people, 14.29%)
- Magnesium (3 people, 14.29%)
- Vitamin C (3 people, 14.29%)
- Amlodipine (3 people, 14.29%)
- Escitalopram (3 people, 14.29%)
- Zeaxanthin (2 people, 9.52%)
- Coenzyme Q10 (2 people, 9.52%)
- Crestor (2 people, 9.52%)
- Nexium 24hr (2 people, 9.52%)
- Ninlaro (2 people, 9.52%)
- Cod Liver Oil (2 people, 9.52%)
- Meclizine (2 people, 9.52%)
Drug effectiveness *:
Famotidine:
n/a
Mounjaro:
n/a
Metformin:
n/a
Chlorthalidone:
n/a
* Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Drug side effects in long term, by gender and age:
- Chlorthalidone: 12,482 reports
- Famotidine: 83,423 reports
- Metformin: 465,355 reports
- Mounjaro: 37,669 reports
Treatments, associated medications and conditions:
- Abnormal dreams: 33,379 reports
- Ankle pain: 294 reports
- Diabetes: 466,616 reports
- Fatigue: 967,539 reports
- High blood pressure: 1,062,858 reports
- Joint pain: 542,935 reports
- Low back pain: 6,978 reports
- Pain - knee: 1,005 reports
- Reflux: 445,836 reports
Drug side effects:
- Famotidine and Low back pain
- Mounjaro and Low back pain
- Metformin and Low back pain
- Chlorthalidone and Low back pain
- Famotidine and Pain - knee
- Mounjaro and Pain - knee
- Metformin and Pain - knee
- Chlorthalidone and Pain - knee
- Famotidine and Joint pain (2,304 reports)
- Mounjaro and Joint pain (185 reports)
- Metformin and Joint pain (12,918 reports)
- Chlorthalidone and Joint pain (540 reports)
- Famotidine and Abnormal dreams (64 reports)
- Mounjaro and Abnormal dreams (21 reports)
- Metformin and Abnormal dreams (716 reports)
- Chlorthalidone and Abnormal dreams (19 reports)
- Famotidine and Fatigue (4,913 reports)
- Mounjaro and Fatigue (801 reports)
- Metformin and Fatigue (26,430 reports)
- Chlorthalidone and Fatigue (1,020 reports)
- Famotidine and Ankle pain
- Mounjaro and Ankle pain
- Metformin and Ankle pain
- Chlorthalidone and Ankle pain
Drug interactions:
- Famotidine and Mounjaro drug interaction (64 reports)
- Famotidine and Metformin drug interaction (5,339 reports)
- Famotidine and Chlorthalidone drug interaction (354 reports)
- Mounjaro and Metformin drug interaction (1,728 reports)
- Mounjaro and Chlorthalidone drug interaction (12 reports)
- Metformin and Chlorthalidone drug interaction (1,794 reports)
Symptoms:
- Reflux and Low back pain
- Reflux and Pain - knee
- Reflux and Joint pain (5,561 reports)
- Reflux and Abnormal dreams (345 reports)
- Reflux and Fatigue (8,750 reports)
- Reflux and Ankle pain
- Diabetes and Low back pain
- Diabetes and Pain - knee
- Diabetes and Joint pain (5,978 reports)
- Diabetes and Abnormal dreams (400 reports)
- Diabetes and Fatigue (10,810 reports)
- Diabetes and Ankle pain
- High blood pressure and Low back pain
- High blood pressure and Pain - knee
- High blood pressure and Joint pain (17,869 reports)
- High blood pressure and Abnormal dreams (1,207 reports)
- High blood pressure and Fatigue (30,608 reports)
- High blood pressure and Ankle pain
Drugs that are associated with:
- Low back pain: 27 drugs
- Pain - knee: 0 drugs
- Joint pain: 3,328 drugs
- Abnormal dreams: 1,091 drugs
- Fatigue: 4,027 drugs
- Ankle pain: 0 drugs
Conditions that are associated with:
- Low back pain: 186 conditions
- Pain - knee: 23 conditions
- Joint pain: 5,212 conditions
- Abnormal dreams: 1,261 conditions
- Fatigue: 6,382 conditions
- Ankle pain: 2 conditions
How the phase IV clinical study uses the data?
The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Omeprazole cause Atrial Fibrillation/Flutter? - 3 seconds ago
- Could Clopidogrel Bisulfate cause Muscle Cramps? - 6 seconds ago
- Could Etoposide cause Chronic Kidney Disease? - 10 seconds ago
- Could Albuterol cause Failure To Thrive? - 11 seconds ago
- Drug interactions of Camphor and Acyclovir - 15 seconds ago
- Could Azelastine cause Hypotension Aggravated? - 16 seconds ago
- Could Pulmozyme cause Dyspnea Exacerbated? - 17 seconds ago
- Could Atacand cause Dyskinesia? - 19 seconds ago
- Escitalopram and Drug Intolerance for Men aged 50-59 - 21 seconds ago
- Celebrex and Gastritis Erosive for Women aged 50-59 - 22 seconds ago