A study for a 55 year old woman who takes Cymbalta, Metformin Hydrochloride, Synthroid, Rosuvastatin Calcium, Losartan Potassium, Pregabalin (an AI-powered real world drug study)
Summary:
59 females aged 55 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 55 year old female patient who has Hashimoto's Disease, High Cholesterol, Diabetes, Fibromyalgia. The study is created by eHealthMe based on reports from sources including the FDA.
59 females aged 55 (±5) who take Cymbalta, Metformin Hydrochloride, Synthroid, Rosuvastatin Calcium, Losartan Potassium, Pregabalin and have adverse effects are studied.
Number of reports submitted per year:

Information of the patient in this study:
- Age: 55
- Gender: female
What are the drugs?
- Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,974 Cymbalta users. Check the latest studies of Cymbalta.
- Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 58,646 Metformin hydrochloride users. Check the latest studies of Metformin hydrochloride.
- Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,202 Synthroid users. Check the latest studies of Synthroid.
- Rosuvastatin calcium has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 25,354 Rosuvastatin calcium users. Check the latest studies of Rosuvastatin calcium.
- Losartan potassium has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 51,513 Losartan potassium users. Check the latest studies of Losartan potassium.
- Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.
What are the conditions?
- Hashimoto's disease (spectrum of autoimmune thyroid diseases (aitds) and is characterized by the destruction of thyroid cells) is found to be associated with 696 drugs and 1,093 conditions by eHealthMe. Check the latest studies of Hashimoto's disease.
- High cholesterol is found to be associated with 3,077 drugs and 3,630 conditions by eHealthMe. Check the latest studies of High cholesterol.
- Diabetes is found to be associated with 2,010 drugs and 2,858 conditions by eHealthMe. Check the latest studies of Diabetes.
- Fibromyalgia (a long-term condition which causes pain all over the body) is found to be associated with 1,335 drugs and 1,836 conditions by eHealthMe. Check the latest studies of Fibromyalgia.
What are the adverse effects?
- Atrophic vaginitis: no further information found. Check the latest studies of Atrophic vaginitis.
Comparison with patient's specific adverse outcomes:
You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.
By the same drug(s):
-
Atrophic Vaginitis (thinning, drying and inflammation of the vaginal walls):
- among females aged 55 (±5) who take the same drugs: 0% (0 of 59)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 360)
By each condition:
-
people who have Atrophic Vaginitis with Fibromyalgia:
- among females aged 55 (±5) who have Fibromyalgia: 0% (0 of 13,478)
- among people who have Fibromyalgia, regardless of gender or age: 0% (0 of 57,409) -
people who have Atrophic Vaginitis with Diabetes:
- among females aged 55 (±5) who have Diabetes: 0% (0 of 29,389)
- among people who have Diabetes, regardless of gender or age: 0% (0 of 367,724) -
people who have Atrophic Vaginitis with Hashimoto's Disease:
- among females aged 55 (±5) who have Hashimoto's Disease: 0% (0 of 1,249)
- among people who have Hashimoto's Disease, regardless of gender or age: 0% (0 of 7,405) -
people who have Atrophic Vaginitis with High Cholesterol:
- among females aged 55 (±5) who have High Cholesterol: 0% (0 of 34,999)
- among people who have High Cholesterol, regardless of gender or age: 0% (0 of 360,958)
By each drug (FDA data only):
-
people who take Cymbalta and have Atrophic Vaginitis:
- among females aged 55 (±5) who take Cymbalta and have side effects: 0% (0 of 21,937)
- among people who take Cymbalta and have side effects, regardless of gender or age: 0% (0 of 145,283) -
people who take Metformin Hydrochloride and have Atrophic Vaginitis:
- among females aged 55 (±5) who take Metformin Hydrochloride and have side effects: 0% (0 of 4,627)
- among people who take Metformin Hydrochloride and have side effects, regardless of gender or age: 0% (0 of 54,793) -
people who take Synthroid and have Atrophic Vaginitis:
- among females aged 55 (±5) who take Synthroid and have side effects: 0% (0 of 33,359)
- among people who take Synthroid and have side effects, regardless of gender or age: 0% (0 of 237,813) -
people who take Rosuvastatin Calcium and have Atrophic Vaginitis:
- among females aged 55 (±5) who take Rosuvastatin Calcium and have side effects: 0% (0 of 2,275)
- among people who take Rosuvastatin Calcium and have side effects, regardless of gender or age: 0% (0 of 24,757) -
people who take Losartan Potassium and have Atrophic Vaginitis:
- among females aged 55 (±5) who take Losartan Potassium and have side effects: 0% (0 of 4,004)
- among people who take Losartan Potassium and have side effects, regardless of gender or age: 0% (0 of 50,029) -
people who take Pregabalin and have Atrophic Vaginitis:
- among females aged 55 (±5) who take Pregabalin and have side effects: 0% (0 of 7,779)
- among people who take Pregabalin and have side effects, regardless of gender or age: 0% (0 of 73,061)
Common drug interactions *:
- Diarrhea : 9 people, 15.25%
- Nausea (feeling of having an urge to vomit): 7 people, 11.86%
- Acute Kidney Failure : 7 people, 11.86%
- Fatigue (feeling of tiredness): 6 people, 10.17%
- Fever : 6 people, 10.17%
- Chronic Kidney Disease : 5 people, 8.47%
- Fall : 4 people, 6.78%
- Cutaneous Vasculitis (an inflammatory process affecting the vessel wall that leads to its damage): 4 people, 6.78%
- Muscle Aches (muscle pain): 4 people, 6.78%
- Memory Loss : 4 people, 6.78%
- Rash Pruritic (redness with itching): 4 people, 6.78%
- Cardiac Disorder : 4 people, 6.78%
- Abdominal Pain : 4 people, 6.78%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 6.78%
- Hair Loss : 4 people, 6.78%
- Injection Site Pain : 4 people, 6.78%
- Head Injury : 4 people, 6.78%
- Weakness : 4 people, 6.78%
- Loss Of Consciousness : 3 people, 5.08%
- Malaise (a feeling of general discomfort or uneasiness): 3 people, 5.08%
Common co-existing conditions *:
You may use this to check any potential undetected conditions.
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 16.95%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 11.86%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 8.47%
- Neuropathy Peripheral (surface nerve damage): 4 people, 6.78%
- Insomnia (sleeplessness): 4 people, 6.78%
- Hypersensitivity : 4 people, 6.78%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 6.78%
- Muscle Spasms (muscle contraction): 4 people, 6.78%
- Weight Loss : 3 people, 5.08%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.08%
- Constipation : 3 people, 5.08%
- Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.08%
- Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 5.08%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 5.08%
- Chest Pain : 2 people, 3.39%
- Breast Cancer Female : 2 people, 3.39%
- Breast Cancer : 2 people, 3.39%
- Blood Potassium Abnormal : 2 people, 3.39%
- Blood Insulin Abnormal : 2 people, 3.39%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 3.39%
Common co-used drugs *:
You may use this to check any potential interacting drugs.
- Vitamin D3 (15 people, 25.42%)
- Pantoprazole (13 people, 22.03%)
- Nexium (12 people, 20.34%)
- Lexapro (9 people, 15.25%)
- Singulair (8 people, 13.56%)
- Xyrem (8 people, 13.56%)
- Hydrochlorothiazide (8 people, 13.56%)
- Celebrex (7 people, 11.86%)
- Victoza (7 people, 11.86%)
- Byetta (7 people, 11.86%)
- Klonopin (7 people, 11.86%)
- Dexilant (7 people, 11.86%)
- Lasix (7 people, 11.86%)
- Zanaflex (7 people, 11.86%)
- Hydrocodone (6 people, 10.17%)
- Risperdal (6 people, 10.17%)
- Premarin (6 people, 10.17%)
- Ondansetron (6 people, 10.17%)
- Morphine (6 people, 10.17%)
- Fish Oil (6 people, 10.17%)
Drug effectiveness *:
Cymbalta:
n/a
Metformin Hydrochloride:
n/a
Synthroid:
n/a
Rosuvastatin Calcium:
n/a
Losartan Potassium:
n/a
Pregabalin:
n/a
* Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Drug side effects in long term, by gender and age:
- Cymbalta: 154,974 reports
- Losartan potassium: 51,513 reports
- Metformin hydrochloride: 58,646 reports
- Pregabalin: 74,070 reports
- Rosuvastatin calcium: 25,354 reports
- Synthroid: 249,202 reports
Treatments, associated medications and conditions:
- Atrophic vaginitis: 51 reports
- Diabetes: 466,616 reports
- Fibromyalgia: 92,989 reports
- Hashimoto's disease: 13,328 reports
- High cholesterol: 478,585 reports
Drug side effects:
- Cymbalta and Atrophic vaginitis
- Metformin hydrochloride and Atrophic vaginitis
- Synthroid and Atrophic vaginitis
- Rosuvastatin calcium and Atrophic vaginitis
- Losartan potassium and Atrophic vaginitis
- Pregabalin and Atrophic vaginitis
Drug interactions:
- Cymbalta and Metformin hydrochloride drug interaction (915 reports)
- Cymbalta and Synthroid drug interaction (9,176 reports)
- Cymbalta and Rosuvastatin calcium drug interaction (594 reports)
- Cymbalta and Losartan potassium drug interaction (1,191 reports)
- Cymbalta and Pregabalin drug interaction (1,194 reports)
- Metformin hydrochloride and Synthroid drug interaction (1,454 reports)
- Metformin hydrochloride and Rosuvastatin calcium drug interaction (1,473 reports)
- Metformin hydrochloride and Losartan potassium drug interaction (1,962 reports)
- Metformin hydrochloride and Pregabalin drug interaction (1,006 reports)
- Synthroid and Rosuvastatin calcium drug interaction (1,797 reports)
- Synthroid and Losartan potassium drug interaction (1,978 reports)
- Synthroid and Pregabalin drug interaction (1,449 reports)
- Rosuvastatin calcium and Losartan potassium drug interaction (1,010 reports)
- Rosuvastatin calcium and Pregabalin drug interaction (1,132 reports)
- Losartan potassium and Pregabalin drug interaction (89 reports)
Symptoms:
- Hashimoto's disease and Atrophic vaginitis
- High cholesterol and Atrophic vaginitis
- Diabetes and Atrophic vaginitis
- Fibromyalgia and Atrophic vaginitis
Drugs that are associated with:
- Atrophic vaginitis: 0 drugs
Conditions that are associated with:
- Atrophic vaginitis: 0 conditions
How the phase IV clinical study uses the data?
The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Humira cause Nasopharyngitis? - 4 seconds ago
- Cisplatin and Lung Cancer Stage Unspecified (Exc Metastatic Tumors To Lung) for Men aged 60+ - 8 seconds ago
- Cisplatin and Lung Cancer Stage Unspecified (Exc Metastatic Tumours To Lung) for Men aged 60+ - 9 seconds ago
- Beyaz vs. Enpresse-28, side effect and effectiveness comparison - 14 seconds ago
- Drug interactions of Excedrin and Cod Liver Oil - 16 seconds ago
- High Blood Pressure and Diabetic Ketoacidosis - 24 seconds ago
- Parkinson'S Disease and Screaming - 40 seconds ago
- Fluvastatin and Dizziness for Men aged 60+ - 42 seconds ago
- Fluvastatin and Lightheadedness for Men aged 60+ - 42 seconds ago
- Fluvastatin and Vertigo for Men aged 60+ - 43 seconds ago