Acetaminophen and codeine phosphate and Hepatic function abnormal - a phase IV clinical study of FDA data

Summary:

Hepatic function abnormal is reported as a side effect among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate), especially for people who are female, 60+ old, also take Allopurinol, and have Gout.

The phase IV clinical study analyzes which people have Hepatic function abnormal when taking Acetaminophen and codeine phosphate. It is created by eHealthMe based on reports of 2,908 people who have side effects when taking Acetaminophen and codeine phosphate from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Hepatic function abnormal?

Hepatic function abnormal is found to be associated with 1,439 drugs and 2,020 conditions by eHealthMe. Check the latest studies of Hepatic function abnormal.

On Jul, 11, 2026

2,908 people reported to have side effects when taking Acetaminophen and codeine phosphate.
Among them, 16 people (0.55%) have Hepatic function abnormal.

Could Acetaminophen and codeine phosphate cause Hepatic function abnormal?

Among these 16 people:

What is the gender of people who have Hepatic function abnormal when taking Acetaminophen and codeine phosphate? *

female: 56.25 %
male: 43.75 %

What is the age of people who have Hepatic function abnormal when taking Acetaminophen and codeine phosphate? *

What are other drugs people take besides Acetaminophen and codeine phosphate? *

What are other side effects people have besides Hepatic function abnormal? *

Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 25.00%
Abdominal Pain Upper: 4 people, 25.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 25.00%
Aspartate Aminotransferase Increased: 3 people, 18.75%
Diarrhea: 3 people, 18.75%
Thrombocytopenia (decrease of platelets in blood): 3 people, 18.75%
Blood Creatine Phosphokinase Increased: 3 people, 18.75%
Hyperkalemia (damage to or disease of the kidney): 3 people, 18.75%
Alanine Aminotransferase Increased: 3 people, 18.75%
Blood Bilirubin Increased: 3 people, 18.75%

What are the existing conditions these people have? *

Gout (uric acid crystals building up in the body): 5 people, 31.25%
Neuralgia (pain in one or more nerves): 4 people, 25.00%
Breast Cancer: 4 people, 25.00%
Suicide Attempt: 2 people, 12.50%
Diarrhea: 1 person, 6.25%
Asthma: 1 person, 6.25%
Benign Neoplasm Of Prostate (benign (non-cancerous) tumours of the prostate): 1 person, 6.25%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%
Diabetes: 1 person, 6.25%
Essential Hypertension (primary hypertension): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and codeine phosphate and have Hepatic function abnormal?

- Check whether Hepatic function abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen and codeine phosphate:

Acetaminophen and codeine phosphate (3,220 reports)

Hepatic function abnormal treatments and more:

Hepatic function abnormal (47,051 reports)

How severe was Hepatic function abnormal and when was it recovered:

Hepatic function abnormal in Acetaminophen and codeine phosphate

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Hepatic function abnormal and drugs with ingredients of acetaminophen; codeine phosphate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen and codeine phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic function abnormal:

Hepatic function abnormal (1,439 drugs)

Browse all the conditions that are associated with Hepatic function abnormal:

Hepatic function abnormal (2,020 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Acetaminophen and codeine phosphate) and Acetaminophen and codeine phosphate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.