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Actiq and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Actiq (fentanyl citrate), especially for people who are male, 50-59 old, have been taking the drug for 6 - 12 months also take Duragesic-100, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Stroke when taking Actiq. It is created by eHealthMe based on reports of 27,560 people who have side effects when taking Actiq from the FDA, and is updated regularly.

What is Actiq?

Actiq has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 27,583 Actiq users. Check the latest studies of Actiq.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,367 drugs and 3,012 conditions by eHealthMe. Check the latest studies of Stroke.

On Jan, 11, 2026

27,560 people reported to have side effects when taking Actiq.
Among them, 24 people (0.09%) have Stroke.

Could Actiq cause Stroke?

Among these 24 people:

How long have people been on Actiq when they have Stroke? *

  • < 1 month: 25 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Stroke when taking Actiq? *

  • female: 20.83 %
  • male: 79.17 %

What is the age of people who have Stroke when taking Actiq? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5.56 %
  • 40-49: 11.11 %
  • 50-59: 77.78 %
  • 60+: 5.56 %

What are other drugs people take besides Actiq? *

  1. Duragesic-100: 15 people, 62.50%
  2. Oxycontin: 14 people, 58.33%
  3. Percocet: 13 people, 54.17%
  4. Neurontin: 12 people, 50.00%
  5. Prilosec: 12 people, 50.00%
  6. Protonix: 11 people, 45.83%
  7. Lantus: 11 people, 45.83%
  8. Duramorph Pf: 11 people, 45.83%
  9. Ms Contin: 11 people, 45.83%
  10. Colace: 11 people, 45.83%

What are other side effects people have besides Stroke? *

  1. Heart Attack: 14 people, 58.33%
  2. Depression: 14 people, 58.33%
  3. Hypoaesthesia (reduced sense of touch or sensation): 12 people, 50.00%
  4. Constipation: 12 people, 50.00%
  5. Dyspnea (difficult or laboured breathing): 12 people, 50.00%
  6. Hyperhidrosis (abnormally increased sweating): 12 people, 50.00%
  7. Bone Pain: 12 people, 50.00%
  8. Pleural Effusion (water on the lungs): 11 people, 45.83%
  9. Rectal Haemorrhage (bleeding from anus): 11 people, 45.83%
  10. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 11 people, 45.83%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 12 people, 50.00%
  2. Neck Pain: 3 people, 12.50%
  3. Back Pain: 2 people, 8.33%
  4. Migraine (headache): 2 people, 8.33%
  5. Stress And Anxiety: 1 person, 4.17%
  6. Dyslipidaemia (abnormal amount of lipids): 1 person, 4.17%
  7. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 4.17%
  8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 4.17%
  9. Cough: 1 person, 4.17%
  10. Depression: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Actiq and have Stroke?

- Check whether Stroke is associated with a drug or a condition (FREE)
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- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actiq:

Stroke treatments and more:

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of fentanyl citrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actiq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Browse all the conditions that are associated with Stroke:

Drugs similar to Actiq and Stroke :

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Actiq) and Actiq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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