Avandia and Intestinal ischaemia - a phase IV clinical study of FDA data
Summary:
Intestinal ischaemia is reported as a side effect among people who take Avandia (rosiglitazone maleate), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Lipitor, and have Breast cancer.
The phase IV clinical study analyzes which people have Intestinal ischaemia when taking Avandia. It is created by eHealthMe based on reports of 141,991 people who have side effects when taking Avandia from the FDA, and is updated regularly.
What is Avandia?
Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 142,155 Avandia users. Check the latest studies of Avandia.
What is Intestinal ischaemia?
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines) is found to be associated with 676 drugs and 834 conditions by eHealthMe. Check the latest studies of Intestinal ischaemia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
141,991 people reported to have side effects when taking Avandia.
Among them, 27 people (0.02%) have Intestinal ischaemia.

Among these 27 people:
How long have people been on Avandia when they have Intestinal ischaemia? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 13.33 %
- 2 - 5 years: 53.33 %
- 5 - 10 years: 33.33 %
- 10+ years: 0.0 %
What is the gender of people who have Intestinal ischaemia when taking Avandia? *
- female: 38.46 %
- male: 61.54 %
What is the age of people who have Intestinal ischaemia when taking Avandia? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 5 %
- 50-59: 20 %
- 60+: 75 %
What are other drugs people take besides Avandia? *
- Simvastatin: 5 people, 18.52%
- Lipitor: 5 people, 18.52%
- Pantoprazole: 4 people, 14.81%
- Glyburide: 4 people, 14.81%
- Atenolol: 4 people, 14.81%
- Bisoprolol Fumarate: 4 people, 14.81%
- Rosuvastatin Calcium: 3 people, 11.11%
- Aspirin: 3 people, 11.11%
- Docetaxel: 3 people, 11.11%
- Omeprazole: 2 people, 7.41%
What are other side effects people have besides Intestinal ischaemia? *
- Cardiac Failure Congestive: 11 people, 40.74%
- Heart Attack: 9 people, 33.33%
- Multi-Organ Failure (multisystem organ failure): 6 people, 22.22%
- Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 14.81%
- Arrhythmias (irregular heartbeat): 4 people, 14.81%
- Septic Shock (shock due to blood infection): 4 people, 14.81%
- Hypotension (abnormally low blood pressure): 3 people, 11.11%
- Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 3 people, 11.11%
- Pulmonary Oedema (fluid accumulation in the lungs): 3 people, 11.11%
- Dyspnea (difficult or laboured breathing): 3 people, 11.11%
What are the existing conditions these people have? *
- Breast Cancer: 3 people, 11.11%
- Stress And Anxiety: 2 people, 7.41%
- High Blood Pressure: 2 people, 7.41%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 3.70%
- Constipation: 1 person, 3.70%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 3.70%
- Depression: 1 person, 3.70%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 3.70%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.70%
- High Blood Cholesterol: 1 person, 3.70%
* Approximation only. Some reports may have incomplete information.
Do you take Avandia and have Intestinal ischaemia?
- Check whether Intestinal ischaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Avandia:
- Avandia (142,155 reports)
Intestinal ischaemia treatments and more:
- Intestinal ischaemia (7,094 reports)
How severe was Intestinal ischaemia and when was it recovered:
Expand to all the drugs that have ingredients of rosiglitazone maleate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Avandia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Intestinal ischaemia:
- Intestinal ischaemia (676 drugs)
Browse all the conditions that are associated with Intestinal ischaemia:
- Intestinal ischaemia (834 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on rosiglitazone maleate (the active ingredients of Avandia) and Avandia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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