Boniva and Lymphoedema - a phase IV clinical study of FDA data
Summary:
Lymphoedema is reported as a side effect among people who take Boniva (ibandronate sodium), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Fosamax, and have Multiple sclerosis.
The phase IV clinical study analyzes which people have Lymphoedema when taking Boniva. It is created by eHealthMe based on reports of 26,949 people who have side effects when taking Boniva from the FDA, and is updated regularly.
What is Boniva?
Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.
What is Lymphoedema?
Lymphoedema (localized fluid retention and tissue swelling) is found to be associated with 912 drugs and 743 conditions by eHealthMe. Check the latest studies of Lymphoedema.
26,949 people reported to have side effects when taking Boniva.
Among them, 35 people (0.13%) have Lymphoedema.

Among these 35 people:
How long have people been on Boniva when they have Lymphoedema? *
- < 1 month: 0.0 %
- 1 - 6 months: 22.22 %
- 6 - 12 months: 11.11 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 55.56 %
- 5 - 10 years: 11.11 %
- 10+ years: 0.0 %
What is the gender of people who have Lymphoedema when taking Boniva? *
- female: 100 %
- male: 0.0 %
What is the age of people who have Lymphoedema when taking Boniva? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 5.56 %
- 50-59: 66.67 %
- 60+: 27.78 %
What are other drugs people take besides Boniva? *
- Fosamax: 24 people, 68.57%
- Evista: 5 people, 14.29%
- Aromasin: 4 people, 11.43%
- Vitamins: 4 people, 11.43%
- Cipro: 4 people, 11.43%
- Zometa: 3 people, 8.57%
- Lorazepam: 3 people, 8.57%
- Actonel: 3 people, 8.57%
- Ampyra: 3 people, 8.57%
- Aspirin: 3 people, 8.57%
What are other side effects people have besides Lymphoedema? *
- Femur Fracture: 21 people, 60.00%
- Pain In Extremity: 19 people, 54.29%
- Fall: 18 people, 51.43%
- Depression: 17 people, 48.57%
- Joint Pain: 17 people, 48.57%
- Hyperlipidaemia (presence of excess lipids in the blood): 16 people, 45.71%
- Stress And Anxiety: 16 people, 45.71%
- Low Turnover Osteopathy (slow removal of old bone and its replacement by new bone): 16 people, 45.71%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 14 people, 40.00%
- Dizziness: 13 people, 37.14%
What are the existing conditions these people have? *
- Stress And Anxiety: 4 people, 11.43%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 11.43%
- Breast Cancer: 3 people, 8.57%
- Menopausal Symptoms: 2 people, 5.71%
- High Blood Pressure: 2 people, 5.71%
- Gait Disturbance: 2 people, 5.71%
- Senile Osteoporosis (weak bones with ageing): 1 person, 2.86%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.86%
- Menopause (end of monthly cycles in women): 1 person, 2.86%
- Inflammatory Bowel Disease: 1 person, 2.86%
* Approximation only. Some reports may have incomplete information.
Do you take Boniva and have Lymphoedema?
- Check whether Lymphoedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Boniva:
- Boniva (27,340 reports)
Lymphoedema treatments and more:
- Lymphoedema (9,453 reports)
How severe was Lymphoedema and when was it recovered:
Expand to all the drugs that have ingredients of ibandronate sodium:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Boniva:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Lymphoedema:
- Lymphoedema (912 drugs)
Browse all the conditions that are associated with Lymphoedema:
- Lymphoedema (743 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ibandronate sodium (the active ingredients of Boniva) and Boniva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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