Raltegravir and Epivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Raltegravir (raltegravir) and Epivir (lamivudine). Common drug interactions include amyloidosis among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Raltegravir and Epivir. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Raltegravir?

Raltegravir has active ingredients of raltegravir. eHealthMe is studying from 5,054 Raltegravir users. Check the latest studies of Raltegravir.

What is Epivir?

Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.

On Jul, 21, 2026

40 people who take Raltegravir and Epivir together, and have interactions are studied.

Raltegravir and Epivir drug interactions.

What are the common drug interactions of Raltegravir and Epivir, by gender? *:

female:

Amyloidosis (a tumour within which amyloid is produced)
Anuria (failure of the kidneys to produce urine)
Arthralgia (joint pain)
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Bone density decreased
Cardiac arrest
Cardiac failure congestive
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Cough

male:

Emotional distress
Pain
Campylobacter gastroenteritis (infection of gastrointestinal system)
Dyslipidaemia (abnormal amount of lipids)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemoglobin decreased
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Herpes zoster
Malaise (a feeling of general discomfort or uneasiness)
Oropharyngeal discomfort (pain or irritation of oropharynx)

What are the common drug interactions of Raltegravir and Epivir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal distension
Anaemia (lack of blood)
Atrioventricular block second degree (heart block second degree)
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Campylobacter gastroenteritis (infection of gastrointestinal system)
Dyslipidaemia (abnormal amount of lipids)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemoglobin decreased
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

30-39:

Device expulsion
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
Kaposi's sarcoma aids related (a tumour caused by human herpes virus associated with aids)
Multi-organ failure (multisystem organ failure)
Pancreatitis (inflammation of pancreas)
Pleural effusion (water on the lungs)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Amylase increased
Death

40-49:

Renal transplant
Renal tubular disorder (disease of kidney tubules)
Respiratory distress (difficulty in breathing)
Thrombocytopenia (decrease of platelets in blood)
Troponin increased
Upper limb fracture
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Vitamin d deficiency
Vomiting
Weight decreased

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Blood creatinine increased
Decreased activity
Fatigue (feeling of tiredness)
Fear
Osteopenia (a condition where bone mineral density is lower than normal)

60+:

Renal failure (kidney dysfunction)
Foot fracture
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Rib fracture
Chills (felling of cold)
Hypersensitivity
Pancreas infection

What are the existing conditions these people have? *

Hiv Infection: 38 people, 95.00%
Anaemia (lack of blood): 7 people, 17.50%
Pain: 7 people, 17.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.00%
Infection: 4 people, 10.00%
Diarrhea: 4 people, 10.00%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 10.00%
Abdominal Distension: 4 people, 10.00%
Lower Gastrointestinal Haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding): 4 people, 10.00%
Depression: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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