Casodex and Multi-organ failure - a phase IV clinical study of FDA data

Summary:

Multi-organ failure is reported as a side effect among people who take Casodex (bicalutamide), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Oxycontin, and have High blood pressure.

The phase IV clinical study analyzes which people have Multi-organ failure when taking Casodex. It is created by eHealthMe based on reports of 10,594 people who have side effects when taking Casodex from the FDA, and is updated regularly.

What is Casodex?

Casodex has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 10,725 Casodex users. Check the latest studies of Casodex.

What is Multi-organ failure?

Multi-organ failure (multisystem organ failure) is found to be associated with 1,384 drugs and 2,281 conditions by eHealthMe. Check the latest studies of Multi-organ failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

10,594 people reported to have side effects when taking Casodex.
Among them, 21 people (0.2%) have Multi-organ failure.

Could Casodex cause Multi-organ failure?

Among these 21 people:

How long have people been on Casodex when they have Multi-organ failure? *

What is the gender of people who have Multi-organ failure when taking Casodex? *

female: 0.0 %
male: 100 %

What is the age of people who have Multi-organ failure when taking Casodex? *

What are other drugs people take besides Casodex? *

What are other side effects people have besides Multi-organ failure? *

Acute Hepatic Failure: 3 people, 14.29%
Interstitial Lung Disease: 3 people, 14.29%
Ascites (accumulation of fluid in the abdominal cavity): 2 people, 9.52%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 2 people, 9.52%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 9.52%
Consciousness - Decreased: 2 people, 9.52%
Infectious Peritonitis (inflammation of the peritoneum, typically caused by bacterial infection): 2 people, 9.52%
Cardiac Arrest: 2 people, 9.52%
Interstitial Pneumonia (lung disease characterized by progressive scarring of both lungs): 2 people, 9.52%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 2 people, 9.52%

What are the existing conditions these people have? *

Cancer Pain: 4 people, 19.05%
High Blood Pressure: 4 people, 19.05%
Prostate Cancer Metastatic: 3 people, 14.29%
Enlarged Prostate: 3 people, 14.29%
Gastritis (inflammation of stomach): 3 people, 14.29%
Insomnia (sleeplessness): 2 people, 9.52%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 9.52%
Prostate Cancer Stage Iv: 2 people, 9.52%
Weight Decreased: 1 person, 4.76%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Casodex and have Multi-organ failure?

- Check whether Multi-organ failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Casodex:

Casodex (10,725 reports)

Browse all side effects of Casodex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multi-organ failure:

Multi-organ failure (1,384 drugs)

Browse all the conditions that are associated with Multi-organ failure:

Multi-organ failure (2,281 conditions)

Related publications that referenced our studies

Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on bicalutamide (the active ingredients of Casodex) and Casodex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.