Cipro and Orchitis - a phase IV clinical study of FDA data


Orchitis is found among people who take Cipro, especially for people who are 60+ old.

The phase IV clinical study analyzes which people take Cipro and have Orchitis. It is created by eHealthMe based on reports of 27,732 people who have side effects when taking Cipro from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 22, 2022

27,732 people reported to have side effects when taking Cipro.
Among them, 17 people (0.06%) have Orchitis.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 29,947 Cipro users for its effectiveness, alternative drugs and more.

What is Orchitis?

Orchitis (inflammation of the testes) is found to be associated with 598 drugs and 375 conditions by eHealthMe.

Number of Cipro and Orchitis reports submitted per year:

Could Cipro cause Orchitis?

Age of people who have Orchitis when taking Cipro *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 12.5 %
  • 40-49: 25.0 %
  • 50-59: 31.25 %
  • 60+: 31.25 %

Common drugs people take besides Cipro *:

  1. Lantus: 5 people, 29.41%
  2. Nexium: 4 people, 23.53%
  3. Avodart: 4 people, 23.53%
  4. Augmentin: 3 people, 17.65%
  5. Bactrim: 3 people, 17.65%
  6. Diclofenac: 3 people, 17.65%
  7. Ergocalciferol: 3 people, 17.65%
  8. Exjade: 3 people, 17.65%
  9. Farxiga: 3 people, 17.65%
  10. Hctz: 3 people, 17.65%

Common side effects people have besides Orchitis *:

  1. Testicular Pain (pain in testes): 7 people, 41.18%
  2. Hydrocele: 5 people, 29.41%
  3. Epididymitis (pain in the scrotum or testicle): 4 people, 23.53%
  4. Congestive Cardiomyopathy (weakening of heart muscle): 4 people, 23.53%
  5. High Blood Pressure: 4 people, 23.53%
  6. Renal Disorder (kidney disease): 3 people, 17.65%
  7. Fatigue (feeling of tiredness): 3 people, 17.65%
  8. Haemoglobin Decreased: 3 people, 17.65%
  9. Weakness: 3 people, 17.65%
  10. Blood Glucose Increased: 3 people, 17.65%

Common conditions people have *:

  1. Type 2 Diabetes: 5 people, 29.41%
  2. Weight Decreased: 3 people, 17.65%
  3. Hypotension (abnormally low blood pressure): 3 people, 17.65%
  4. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 11.76%
  5. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 11.76%
  6. Nausea And Vomiting: 2 people, 11.76%
  7. Nausea (feeling of having an urge to vomit): 2 people, 11.76%
  8. Infusion Related Reaction: 2 people, 11.76%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
  10. Pancreatic Carcinoma (pancreatic cancer): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Cipro and have Orchitis?

Check whether Orchitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Cipro:

Orchitis treatments and more:

COVID vaccines that are related to Orchitis:

How severe was Orchitis and when was it recovered:

Expand to all the drugs that have ingredients of ciprofloxacin hydrochloride:

All the drugs that are associated with Orchitis:

All the conditions that are associated with Orchitis:

How the study uses the data?

The study uses data from the FDA. It is based on ciprofloxacin hydrochloride (the active ingredients of Cipro) and Cipro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: