Co-codamol and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Co-codamol (acetaminophen; codeine phosphate), especially for people who are female, 60+ old, also take Simvastatin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Stroke when taking Co-codamol. It is created by eHealthMe based on reports of 1,873 people who have side effects when taking Co-codamol from the FDA, and is updated regularly.

What is Co-codamol?

Co-codamol has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 2,361 Co-codamol users. Check the latest studies of Co-codamol.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,382 drugs and 3,009 conditions by eHealthMe. Check the latest studies of Stroke.

On Sep, 20, 2025

1,873 people reported to have side effects when taking Co-codamol.
Among them, 13 people (0.69%) have Stroke.

Among these 13 people:

What is the gender of people who have Stroke when taking Co-codamol? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Stroke when taking Co-codamol? *

What are other drugs people take besides Co-codamol? *

What are other side effects people have besides Stroke? *

Metastases To Liver (cancer spreads to liver): 2 people, 15.38%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 15.38%
Pneumonia: 2 people, 15.38%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 15.38%
Memory Loss: 2 people, 15.38%
Head Injury: 2 people, 15.38%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 7.69%
Duodenitis (inflammation of the duodenum): 1 person, 7.69%
Dyspnea (difficult or laboured breathing): 1 person, 7.69%
Electrocardiogram Qt Prolonged: 1 person, 7.69%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 38.46%
Age-Related Macular Degeneration: 2 people, 15.38%
Depression: 2 people, 15.38%
Metastases To Bone (cancer spreads to bone): 1 person, 7.69%
Asthma: 1 person, 7.69%
Atrophic Vulvovaginitis (inflammation of the vulva): 1 person, 7.69%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 7.69%
Diarrhea: 1 person, 7.69%
Essential Hypertension (primary hypertension): 1 person, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Co-codamol and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Co-codamol:

Co-codamol (2,361 reports)

Stroke treatments and more:

Stroke (334,631 reports)

How severe was Stroke and when was it recovered:

Stroke in Co-codamol

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Stroke and drugs with ingredients of acetaminophen; codeine phosphate (599 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Co-codamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,382 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,009 conditions)

Drugs similar to Co-codamol and Stroke :

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Co-codamol) and Co-codamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.