Comtan and Tremor - a phase IV clinical study of FDA data

Summary:

Tremor is reported as a side effect among people who take Comtan (entacapone), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sinemet, and have Depression.

The phase IV clinical study analyzes which people have Tremor when taking Comtan. It is created by eHealthMe based on reports of 3,900 people who have side effects when taking Comtan from the FDA, and is updated regularly.

What is Comtan?

Comtan has active ingredients of entacapone. It is often used in parkinson's disease. eHealthMe is studying from 3,979 Comtan users. Check the latest studies of Comtan.

What is Tremor?

Tremor (trembling or shaking movements in one or more parts of your body) is found to be associated with 2,643 drugs and 3,730 conditions by eHealthMe. Check the latest studies of Tremor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

3,900 people reported to have side effects when taking Comtan.
Among them, 153 people (3.92%) have Tremor.

Among these 153 people:

* Approximation only. Some reports may have incomplete information.

Do you take Comtan and have Tremor?

- Check whether Tremor is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Comtan:

Comtan (3,979 reports)

Tremor treatments and more:

Tremor (195,267 reports)

How severe was Tremor and when was it recovered:

Tremor in Comtan

Expand to all the drugs that have ingredients of entacapone:

Tremor and drugs with ingredients of entacapone (349 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Comtan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tremor:

Tremor (2,643 drugs)

Browse all the conditions that are associated with Tremor:

Tremor (3,730 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on entacapone (the active ingredients of Comtan) and Comtan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.