Creon and Shoulder operation - a phase IV clinical study of FDA data

Summary:

Shoulder operation is reported as a side effect among people who take Creon (pancrelipase (amylase;lipase;protease)), especially for people who are male, 50-59 old, also take Tresiba, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Shoulder operation when taking Creon. It is created by eHealthMe based on reports of 29,220 people who have side effects when taking Creon from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Shoulder operation?

Shoulder operation is found to be associated with 390 drugs and 289 conditions by eHealthMe. Check the latest studies of Shoulder operation.



On Jul, 11, 2026

29,220 people reported to have side effects when taking Creon.
Among them, 17 people (0.06%) have Shoulder operation.

Could Creon cause Shoulder operation?

Among these 17 people:

What is the gender of people who have Shoulder operation when taking Creon? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Shoulder operation when taking Creon? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 55.56 %
  • 60+: 44.44 %

What are other drugs people take besides Creon? *

  1. Melatonin: 3 people, 17.65%
  2. Oxycodone And Acetaminophen: 3 people, 17.65%
  3. Tresiba: 3 people, 17.65%
  4. Cayston: 2 people, 11.76%
  5. Lyrica: 2 people, 11.76%
  6. Trikafta: 2 people, 11.76%
  7. Tobi Podhaler: 2 people, 11.76%
  8. Humalog: 2 people, 11.76%
  9. Selenium: 2 people, 11.76%
  10. Humira: 1 person, 5.88%

What are other side effects people have besides Shoulder operation? *

  1. Stress And Anxiety: 3 people, 17.65%
  2. Abdominal Pain Upper: 2 people, 11.76%
  3. Photophobia (extreme sensitivity to light): 2 people, 11.76%
  4. Depression: 2 people, 11.76%
  5. Nausea (feeling of having an urge to vomit): 2 people, 11.76%
  6. Nausea And Vomiting: 2 people, 11.76%
  7. Pain: 2 people, 11.76%
  8. Hospitalisation: 2 people, 11.76%
  9. Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 2 people, 11.76%
  10. Cataract (clouding of the lens inside the eye): 1 person, 5.88%

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 2 people, 11.76%
  2. Urinary Tract Disorder: 1 person, 5.88%
  3. Iron Deficiency: 1 person, 5.88%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
  5. High Blood Pressure: 1 person, 5.88%
  6. Hypoaesthesia (reduced sense of touch or sensation): 1 person, 5.88%
  7. Hypoaesthesia Eye (reduced sense of touch or sensation on eyes): 1 person, 5.88%
  8. Insomnia (sleeplessness): 1 person, 5.88%
  9. Neuralgia (pain in one or more nerves): 1 person, 5.88%
  10. Stress And Anxiety: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Creon and have Shoulder operation?

- Check whether Shoulder operation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Creon:

Shoulder operation treatments and more:

How severe was Shoulder operation and when was it recovered:

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Creon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shoulder operation:

Browse all the conditions that are associated with Shoulder operation:


How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Creon) and Creon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: