Escitalopram and Brain death - a phase IV clinical study of FDA data

Summary:

Brain death is reported as a side effect among people who take Escitalopram (escitalopram oxalate), especially for people who are male, 20-29 old, also take Paracetamol, and have Suicide attempt.

The study is created by eHealthMe based on reports of 75,134 people who have side effects when taking Escitalopram from the FDA, and is updated regularly.

What is Escitalopram?

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,080 Escitalopram users. Check the latest studies of Escitalopram.

On Jul, 06, 2026

75,134 people reported to have side effects when taking Escitalopram.
Among them, 30 people (0.04%) died.

Among these 30 people:

What is the gender of people who died when taking Escitalopram? *

female: 21.43 %
male: 78.57 %

What is the age of people who died when taking Escitalopram? *

What are other drugs people take besides Escitalopram? *

What are other side effects people have before they died? *

Ventricular Fibrillation (abnormally irregular heart rhythm): 14 people, 46.67%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 11 people, 36.67%
Cardiac Fibrillation (uncontrolled muscle contraction of heart): 10 people, 33.33%
Suicide Attempt: 8 people, 26.67%
Completed Suicide (act of taking one's own life): 8 people, 26.67%
Consciousness - Decreased: 8 people, 26.67%
Electrocardiogram Qrs Complex Prolonged: 7 people, 23.33%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 7 people, 23.33%
Distributive Shock (hock caused by poor distribution of the blood flow): 7 people, 23.33%
Overdose: 6 people, 20.00%

What are the existing conditions these people have? *

Suicide Attempt: 6 people, 20.00%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 13.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 13.33%
Fungal Abscess Central Nervous System (collection of pus in brain by result of fungal infection): 4 people, 13.33%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 3 people, 10.00%
Electrocardiogram Qrs Complex Abnormal: 3 people, 10.00%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.33%
Parkinson's Disease: 1 person, 3.33%
Electrocardiogram Qrs Complex Prolonged: 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Escitalopram:

Escitalopram (78,080 reports)

Expand to all the drugs that have ingredients of escitalopram oxalate:

Brain death and drugs with ingredients of escitalopram oxalate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Escitalopram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain death:

Brain death (320 drugs)

Browse all the conditions that are associated with Brain death:

Brain death (489 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate (the active ingredients of Escitalopram) and Escitalopram (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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