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Glucophage and Alpha 1 foetoprotein increased - a phase IV clinical study of FDA data

Summary:

Alpha 1 foetoprotein increased is reported as a side effect among people who take Glucophage (metformin hydrochloride), especially for people who are male, 60+ old, also take Clozaril, and have Schizophrenia.

The phase IV clinical study analyzes which people have Alpha 1 foetoprotein increased when taking Glucophage. It is created by eHealthMe based on reports of 59,839 people who have side effects when taking Glucophage from the FDA, and is updated regularly.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

What is Alpha 1 foetoprotein increased?

Alpha 1 foetoprotein increased is found to be associated with 121 drugs and 205 conditions by eHealthMe. Check the latest studies of Alpha 1 foetoprotein increased.

On Jul, 15, 2026

59,839 people reported to have side effects when taking Glucophage.
Among them, 16 people (0.03%) have Alpha 1 foetoprotein increased.

Could Glucophage cause Alpha 1 foetoprotein increased?

Among these 16 people:

What is the gender of people who have Alpha 1 foetoprotein increased when taking Glucophage? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Alpha 1 foetoprotein increased when taking Glucophage? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 6.67 %
  • 50-59: 13.33 %
  • 60+: 80.0 %

What are other drugs people take besides Glucophage? *

  1. Lipitor: 6 people, 37.50%
  2. Rezulin: 6 people, 37.50%
  3. Ramipril: 6 people, 37.50%
  4. Clozaril: 6 people, 37.50%
  5. Aspirin: 5 people, 31.25%
  6. Citalopram Hydrobromide: 4 people, 25.00%
  7. Glucotrol Xl: 3 people, 18.75%
  8. Vitamin E: 3 people, 18.75%
  9. Premarin: 3 people, 18.75%
  10. Naprosyn: 3 people, 18.75%

What are other side effects people have besides Alpha 1 foetoprotein increased? *

  1. High Blood Cholesterol: 9 people, 56.25%
  2. Hepatic Neoplasm Malignant (liver cancer): 7 people, 43.75%
  3. High Blood Pressure: 6 people, 37.50%
  4. Weight Loss: 6 people, 37.50%
  5. Liver Function Test Abnormal: 5 people, 31.25%
  6. Blood Albumin Decreased: 4 people, 25.00%
  7. Aortic Aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall): 4 people, 25.00%
  8. Ascites (accumulation of fluid in the abdominal cavity): 4 people, 25.00%
  9. Activated Partial Thromboplastin Time Prolonged: 4 people, 25.00%
  10. Portal Hypertension (increase in the blood pressure within a system of veins called the portal venous system): 3 people, 18.75%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 37.50%
  2. High Blood Cholesterol: 5 people, 31.25%
  3. High Blood Pressure: 4 people, 25.00%
  4. Depression: 4 people, 25.00%
  5. Heart Disease: 3 people, 18.75%
  6. Hepatitis C: 1 person, 6.25%
  7. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Glucophage and have Alpha 1 foetoprotein increased?

- Check whether Alpha 1 foetoprotein increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glucophage:

Alpha 1 foetoprotein increased treatments and more:

How severe was Alpha 1 foetoprotein increased and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glucophage:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Alpha 1 foetoprotein increased:

Browse all the conditions that are associated with Alpha 1 foetoprotein increased:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Glucophage) and Glucophage (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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