Hydrodiuril and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Hydrodiuril (hydrochlorothiazide), especially for people who are male, 60+ old, also take Vioxx, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Irritability when taking Hydrodiuril. It is created by eHealthMe based on reports of 4,135 people who have side effects when taking Hydrodiuril from the FDA, and is updated regularly.

What is Hydrodiuril?

Hydrodiuril has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,211 Hydrodiuril users. Check the latest studies of Hydrodiuril.

What is Irritability?

Irritability is found to be associated with 1,700 drugs and 2,458 conditions by eHealthMe. Check the latest studies of Irritability.

On Jul, 19, 2026

4,135 people reported to have side effects when taking Hydrodiuril.
Among them, 15 people (0.36%) have Irritability.

Among these 15 people:

What is the gender of people who have Irritability when taking Hydrodiuril? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Irritability when taking Hydrodiuril? *

What are other drugs people take besides Hydrodiuril? *

What are other side effects people have besides Irritability? *

Stress And Anxiety: 15 people, 100.00%
Fatigue (feeling of tiredness): 14 people, 93.33%
Insomnia (sleeplessness): 12 people, 80.00%
Memory Loss: 11 people, 73.33%
Back Pain: 9 people, 60.00%
Weakness: 8 people, 53.33%
Fall: 8 people, 53.33%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 7 people, 46.67%
Oedema Peripheral (superficial swelling): 7 people, 46.67%
Feeling Abnormal: 7 people, 46.67%

What are the existing conditions these people have? *

High Blood Cholesterol: 7 people, 46.67%
Pain In Extremity: 5 people, 33.33%
Oedema Peripheral (superficial swelling): 4 people, 26.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 26.67%
Depression: 4 people, 26.67%
Cellulitis (infection under the skin): 4 people, 26.67%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 20.00%
Pain: 2 people, 13.33%
Nausea And Vomiting: 1 person, 6.67%
Nausea (feeling of having an urge to vomit): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrodiuril and have Irritability?

- Check whether Irritability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrodiuril:

Hydrodiuril (4,211 reports)

Irritability treatments and more:

Irritability (71,614 reports)

Browse all side effects of Hydrodiuril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Irritability (1,700 drugs)

Browse all the conditions that are associated with Irritability:

Irritability (2,458 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hydrodiuril) and Hydrodiuril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.