Inspra and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Inspra (eplerenone), especially for people who are male, 60+ old, also take Coreg, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Stroke when taking Inspra. It is created by eHealthMe based on reports of 3,456 people who have side effects when taking Inspra from the FDA, and is updated regularly.

What is Inspra?

Inspra has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 3,510 Inspra users. Check the latest studies of Inspra.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,396 drugs and 3,006 conditions by eHealthMe. Check the latest studies of Stroke.

On Aug, 19, 2025

3,456 people reported to have side effects when taking Inspra.
Among them, 46 people (1.33%) have Stroke.

Among these 46 people:

What is the gender of people who have Stroke when taking Inspra? *

female: 22.73 %
male: 77.27 %

What is the age of people who have Stroke when taking Inspra? *

What are other drugs people take besides Inspra? *

What are other side effects people have besides Stroke? *

Diastolic Dysfunction: 6 people, 13.04%
Speech Impairment (Adult) (inability to speak (adult)): 5 people, 10.87%
Fall: 5 people, 10.87%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 10.87%
Loss Of Consciousness: 5 people, 10.87%
Cardiac Failure Congestive: 5 people, 10.87%
Mitral Valve Incompetence (inefficient heart valve): 4 people, 8.70%
Fatigue (feeling of tiredness): 4 people, 8.70%
Hypotension (abnormally low blood pressure): 4 people, 8.70%
Carotid Artery Disease: 4 people, 8.70%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 13.04%
Cardiac Failure: 4 people, 8.70%
Pain: 3 people, 6.52%
Diabetes: 3 people, 6.52%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.52%
Cardiomyopathy (weakening of the heart muscle): 2 people, 4.35%
Depression: 2 people, 4.35%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 4.35%
Erection Problems: 2 people, 4.35%
Type 2 Diabetes: 2 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Inspra and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Inspra:

Inspra (3,510 reports)

Stroke treatments and more:

Stroke (334,630 reports)

Browse all side effects of Inspra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,396 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,006 conditions)

Drugs similar to Inspra and Stroke :

How the study uses the data?

The study uses data from the FDA. It is based on eplerenone (the active ingredients of Inspra) and Inspra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.