Invirase and Osteoporosis - a phase IV clinical study of FDA data

Summary:

Osteoporosis is reported as a side effect among people who take Invirase (saquinavir mesylate), especially for people who are male, 50-59 old, have been taking the drug for 1 - 2 years also take Norvir, and have Hiv infection.

The phase IV clinical study analyzes which people have Osteoporosis when taking Invirase. It is created by eHealthMe based on reports of 2,682 people who have side effects when taking Invirase from the FDA, and is updated regularly.

What is Invirase?

Invirase has active ingredients of saquinavir mesylate. eHealthMe is studying from 2,690 Invirase users. Check the latest studies of Invirase.

What is Osteoporosis?

Osteoporosis (bones weak and more likely to break) is found to be associated with 1,809 drugs and 1,902 conditions by eHealthMe. Check the latest studies of Osteoporosis.

On Jul, 27, 2026

2,682 people reported to have side effects when taking Invirase.
Among them, 100 people (3.73%) have Osteoporosis.

Among these 100 people:

How long have people been on Invirase when they have Osteoporosis? *

What is the gender of people who have Osteoporosis when taking Invirase? *

female: 24.49 %
male: 75.51 %

What is the age of people who have Osteoporosis when taking Invirase? *

What are other drugs people take besides Invirase? *

What are other side effects people have besides Osteoporosis? *

Emotional Distress: 74 people, 74.00%
Pain: 73 people, 73.00%
Stress And Anxiety: 70 people, 70.00%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 69 people, 69.00%
Bone Density Decreased: 43 people, 43.00%
Depression: 35 people, 35.00%
Osteopenia (a condition where bone mineral density is lower than normal): 34 people, 34.00%
Chronic Kidney Disease: 31 people, 31.00%
Acute Kidney Failure: 21 people, 21.00%
Renal Impairment (severely reduced kidney function): 19 people, 19.00%

What are the existing conditions these people have? *

Hiv Infection: 89 people, 89.00%
High Blood Pressure: 12 people, 12.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 11.00%
Pain: 10 people, 10.00%
Stress And Anxiety: 8 people, 8.00%
Depression: 8 people, 8.00%
Nausea (feeling of having an urge to vomit): 8 people, 8.00%
Liver Disorder (liver diseases): 7 people, 7.00%
Tinea Infection (fungal skin infection): 7 people, 7.00%
Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 7 people, 7.00%

* Approximation only. Some reports may have incomplete information.

Do you take Invirase and have Osteoporosis?

- Check whether Osteoporosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Invirase:

Invirase (2,690 reports)

Osteoporosis treatments and more:

Osteoporosis (290,734 reports)

Browse all side effects of Invirase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteoporosis:

Osteoporosis (1,809 drugs)

Browse all the conditions that are associated with Osteoporosis:

Osteoporosis (1,902 conditions)

Related publications that referenced our studies

Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on saquinavir mesylate (the active ingredients of Invirase) and Invirase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.