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Lamictal and Developmental delay - a phase IV clinical study of FDA data

Summary:

Developmental delay is reported as a side effect among people who take Lamictal (lamotrigine), especially for people who are female, 2-9 old, have been taking the drug for 6 - 12 months also take Keppra, and have Foetal exposure during pregnancy.

The phase IV clinical study analyzes which people have Developmental delay when taking Lamictal. It is created by eHealthMe based on reports of 74,218 people who have side effects when taking Lamictal from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.

What is Developmental delay?

Developmental delay is found to be associated with 361 drugs and 428 conditions by eHealthMe. Check the latest studies of Developmental delay.

On Jul, 16, 2026

74,218 people reported to have side effects when taking Lamictal.
Among them, 68 people (0.09%) have Developmental delay.

Could Lamictal cause Developmental delay?

Among these 68 people:

How long have people been on Lamictal when they have Developmental delay? *

  • < 1 month: 9.09 %
  • 1 - 6 months: 18.18 %
  • 6 - 12 months: 45.45 %
  • 1 - 2 years: 18.18 %
  • 2 - 5 years: 9.09 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Developmental delay when taking Lamictal? *

  • female: 59.68 %
  • male: 40.32 %

What is the age of people who have Developmental delay when taking Lamictal? *

  • 0-1: 30.43 %
  • 2-9: 30.43 %
  • 10-19: 4.35 %
  • 20-29: 8.7 %
  • 30-39: 4.35 %
  • 40-49: 0.0 %
  • 50-59: 8.7 %
  • 60+: 4.35 %

What are other drugs people take besides Lamictal? *

  1. Keppra: 20 people, 29.41%
  2. Folic Acid: 14 people, 20.59%
  3. Vimpat: 12 people, 17.65%
  4. Topamax: 12 people, 17.65%
  5. Onfi: 10 people, 14.71%
  6. Felbatol: 8 people, 11.76%
  7. Zonegran: 8 people, 11.76%
  8. Depakene: 8 people, 11.76%
  9. Vistaril: 3 people, 4.41%
  10. Clobazam: 3 people, 4.41%

What are other side effects people have besides Developmental delay? *

  1. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 20 people, 29.41%
  2. Speech Disorder Developmental: 17 people, 25.00%
  3. Memory Loss: 13 people, 19.12%
  4. Learning Disorder (the brain's disability to receive, process, store, respond to and communicate information): 11 people, 16.18%
  5. Hypotonia (low muscle tone): 11 people, 16.18%
  6. Speech Impairment (Adult) (inability to speak (adult)): 11 people, 16.18%
  7. Drug Ineffective: 10 people, 14.71%
  8. Drug Exposure During Pregnancy: 10 people, 14.71%
  9. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 9 people, 13.24%
  10. Motormental Retardation (a slowing-down of thought and a reduction of physical work): 7 people, 10.29%

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 4.41%
  2. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 3 people, 4.41%
  3. Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 2.94%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 2.94%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 2.94%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 2.94%
  7. The Flu (the flu is caused by an influenza virus): 1 person, 1.47%
  8. Stress And Anxiety: 1 person, 1.47%
  9. Pain: 1 person, 1.47%
  10. Mood Swings (an extreme or rapid change in mood): 1 person, 1.47%

* Approximation only. Some reports may have incomplete information.

Do you take Lamictal and have Developmental delay?

- Check whether Developmental delay is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamictal:

Developmental delay treatments and more:

How severe was Developmental delay and when was it recovered:

Expand to all the drugs that have ingredients of lamotrigine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamictal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Developmental delay:

Browse all the conditions that are associated with Developmental delay:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamictal) and Lamictal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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