Lisinopril and Extremity necrosis - a phase IV clinical study of FDA data

Summary:

Extremity necrosis is reported as a side effect among people who take Lisinopril (lisinopril), especially for people who are male, 60+ old, also take Ativan, and have Pain.

The phase IV clinical study analyzes which people have Extremity necrosis when taking Lisinopril. It is created by eHealthMe based on reports of 343,814 people who have side effects when taking Lisinopril from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.

What is Extremity necrosis?

Extremity necrosis (death of body tissue of arms and legs) is found to be associated with 300 drugs and 409 conditions by eHealthMe. Check the latest studies of Extremity necrosis.

On Jul, 18, 2026

343,814 people reported to have side effects when taking Lisinopril.
Among them, 22 people (0.01%) have Extremity necrosis.

Could Lisinopril cause Extremity necrosis?

Among these 22 people:

What is the gender of people who have Extremity necrosis when taking Lisinopril? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Extremity necrosis when taking Lisinopril? *

What are other drugs people take besides Lisinopril? *

What are other side effects people have besides Extremity necrosis? *

Hypotension (abnormally low blood pressure): 8 people, 36.36%
Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 36.36%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 7 people, 31.82%
Heparin-Induced Thrombocytopenia: 6 people, 27.27%
Peripheral Ischaemia (impaired circulation to an extremity): 5 people, 22.73%
Anaemia (lack of blood): 5 people, 22.73%
Thrombocytopenia (decrease of platelets in blood): 5 people, 22.73%
Pneumonia: 4 people, 18.18%
Multi-Organ Failure (multisystem organ failure): 4 people, 18.18%
Injection Site Reaction: 4 people, 18.18%

What are the existing conditions these people have? *

Skin Papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections): 4 people, 18.18%
Pain: 4 people, 18.18%
High Blood Cholesterol: 3 people, 13.64%
Stress And Anxiety: 3 people, 13.64%
Sleep Disorder: 3 people, 13.64%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 13.64%
Bradycardia (abnormally slow heart action): 3 people, 13.64%
Hypoglycemia (low blood sugar): 3 people, 13.64%
Indigestion: 3 people, 13.64%
Nausea And Vomiting: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and have Extremity necrosis?

- Check whether Extremity necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lisinopril:

Lisinopril (358,654 reports)

Browse all side effects of Lisinopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extremity necrosis:

Extremity necrosis (300 drugs)

Browse all the conditions that are associated with Extremity necrosis:

Extremity necrosis (409 conditions)

Related publications that referenced our studies

Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Lisinopril) and Lisinopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.