Lupron and Lymphoedema - a phase IV clinical study of FDA data
Summary:
Lymphoedema is reported as a side effect among people who take Lupron (leuprolide acetate), especially for people who are male, 40-49 old, have been taking the drug for 5 - 10 years also take Zometa, and have Metastases to bone.
The phase IV clinical study analyzes which people have Lymphoedema when taking Lupron. It is created by eHealthMe based on reports of 41,483 people who have side effects when taking Lupron from the FDA, and is updated regularly.
What is Lupron?
Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.
What is Lymphoedema?
Lymphoedema (localized fluid retention and tissue swelling) is found to be associated with 916 drugs and 743 conditions by eHealthMe. Check the latest studies of Lymphoedema.
41,483 people reported to have side effects when taking Lupron.
Among them, 58 people (0.14%) have Lymphoedema.
Among these 58 people:
How long have people been on Lupron when they have Lymphoedema? *
- < 1 month: 16.67 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 16.67 %
- 1 - 2 years: 33.33 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 33.33 %
- 10+ years: 0.0 %
What is the gender of people who have Lymphoedema when taking Lupron? *
- female: 45.61 %
- male: 54.39 %
What is the age of people who have Lymphoedema when taking Lupron? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 4.65 %
- 40-49: 51.16 %
- 50-59: 16.28 %
- 60+: 27.91 %
What are other drugs people take besides Lupron? *
- Zometa: 35 people, 60.34%
- Restoril: 23 people, 39.66%
- Aspirin: 21 people, 36.21%
- Tamoxifen Citrate: 20 people, 34.48%
- Paxil: 18 people, 31.03%
- Ambien: 17 people, 29.31%
- Xanax: 17 people, 29.31%
- Wellbutrin: 17 people, 29.31%
- Multivitamin: 14 people, 24.14%
- Metronidazole: 14 people, 24.14%
What are other side effects people have besides Lymphoedema? *
- Pain: 33 people, 56.90%
- Osteonecrosis Of Jaw (death of bone of jaw): 33 people, 56.90%
- Oedema Peripheral (superficial swelling): 33 people, 56.90%
- Stress And Anxiety: 33 people, 56.90%
- General Physical Health Deterioration (weak health status): 32 people, 55.17%
- Pain In Jaw: 31 people, 53.45%
- Metastases To Bone (cancer spreads to bone): 30 people, 51.72%
- Rashes (redness): 30 people, 51.72%
- Joint Pain: 29 people, 50.00%
- Bone Disorder: 28 people, 48.28%
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 19 people, 32.76%
- Stress And Anxiety: 14 people, 24.14%
- Neoplasm Malignant (cancer tumour): 13 people, 22.41%
- Sleep Disorder: 13 people, 22.41%
- Depression: 13 people, 22.41%
- Breast Cancer Metastatic: 11 people, 18.97%
- Breast Cancer: 3 people, 5.17%
- High Blood Pressure: 2 people, 3.45%
- Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 2 people, 3.45%
- Prostate Cancer Metastatic: 2 people, 3.45%
* Approximation only. Some reports may have incomplete information.
Do you take Lupron and have Lymphoedema?
- Check whether Lymphoedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Lupron:
- Lupron (42,122 reports)
Lymphoedema treatments and more:
- Lymphoedema (9,453 reports)
How severe was Lymphoedema and when was it recovered:
Expand to all the drugs that have ingredients of leuprolide acetate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lupron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Lymphoedema:
- Lymphoedema (916 drugs)
Browse all the conditions that are associated with Lymphoedema:
- Lymphoedema (743 conditions)
Related publications that referenced our studies
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on leuprolide acetate (the active ingredients of Lupron) and Lupron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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