Marcaine and Sepsis - a phase IV clinical study of FDA data

Summary:

Sepsis is reported as a side effect among people who take Marcaine (bupivacaine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Sepsis when taking Marcaine. It is created by eHealthMe based on reports of 3,971 people who have side effects when taking Marcaine from the FDA, and is updated regularly.

What is Marcaine?

Marcaine has active ingredients of bupivacaine hydrochloride. It is often used in pain. eHealthMe is studying from 4,026 Marcaine users. Check the latest studies of Marcaine.

What is Sepsis?

Sepsis (a severe blood infection that can lead to organ failure and death) is found to be associated with 2,522 drugs and 3,259 conditions by eHealthMe. Check the latest studies of Sepsis.

On Jul, 14, 2026

3,971 people reported to have side effects when taking Marcaine.
Among them, 21 people (0.53%) have Sepsis.

Among these 21 people:

How long have people been on Marcaine when they have Sepsis? *

What is the gender of people who have Sepsis when taking Marcaine? *

female: 40 %
male: 60 %

What is the age of people who have Sepsis when taking Marcaine? *

What are other drugs people take besides Marcaine? *

What are other side effects people have besides Sepsis? *

Cellulitis (infection under the skin): 4 people, 19.05%
Acute Kidney Failure: 4 people, 19.05%
Urinary Tract Infection: 3 people, 14.29%
Depression: 3 people, 14.29%
Dyspnea (difficult or laboured breathing): 3 people, 14.29%
Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 14.29%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 14.29%
Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 3 people, 14.29%
Arthritis Bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection): 3 people, 14.29%
Necrotising Fasciitis (an uncommon life-threatening soft-tissue infection): 3 people, 14.29%

What are the existing conditions these people have? *

Type 2 Diabetes: 5 people, 23.81%
Weight Decreased: 3 people, 14.29%
Hypotension (abnormally low blood pressure): 3 people, 14.29%
Depression: 3 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 14.29%
Hypersensitivity: 2 people, 9.52%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 2 people, 9.52%
Gout (uric acid crystals building up in the body): 1 person, 4.76%
Indigestion: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Marcaine and have Sepsis?

- Check whether Sepsis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Marcaine:

Marcaine (4,026 reports)

Sepsis treatments and more:

Sepsis (140,102 reports)

Browse all side effects of Marcaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sepsis:

Sepsis (2,522 drugs)

Browse all the conditions that are associated with Sepsis:

Sepsis (3,259 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bupivacaine hydrochloride (the active ingredients of Marcaine) and Marcaine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.