Msm and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Msm (methylsulfonylmethane), especially for people who are female, 50-59 old, have been taking the drug for 10+ years also take Magnesium, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Weight increased when taking Msm. It is created by eHealthMe based on reports of 978 people who have side effects when taking Msm from the FDA, and is updated regularly.

What is Msm?

Msm has active ingredients of methylsulfonylmethane. It is often used in joint pain. eHealthMe is studying from 1,210 Msm users. Check the latest studies of Msm.

What is Weight increased?

Weight increased is found to be associated with 2,887 drugs and 3,951 conditions by eHealthMe. Check the latest studies of Weight increased.

On Jul, 15, 2026

978 people reported to have side effects when taking Msm.
Among them, 33 people (3.37%) have Weight increased.

Among these 33 people:

How long have people been on Msm when they have Weight increased? *

What is the gender of people who have Weight increased when taking Msm? *

female: 86.21 %
male: 13.79 %

What is the age of people who have Weight increased when taking Msm? *

What are other drugs people take besides Msm? *

What are other side effects people have besides Weight increased? *

Joint Swelling: 12 people, 36.36%
Drug Ineffective: 12 people, 36.36%
Pain: 12 people, 36.36%
Burning Sensation: 11 people, 33.33%
High Blood Cholesterol: 10 people, 30.30%
Fall: 8 people, 24.24%
Fatigue (feeling of tiredness): 7 people, 21.21%
Diabetes: 7 people, 21.21%
Sinusitis (inflammation of sinus): 7 people, 21.21%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 21.21%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 51.52%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 15.15%
Blood Iron Decreased: 3 people, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.09%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 9.09%
Migraine (headache): 2 people, 6.06%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 6.06%
Pain: 2 people, 6.06%
High Blood Pressure: 2 people, 6.06%
Neuralgia (pain in one or more nerves): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Msm and have Weight increased?

- Check whether Weight increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Msm:

Msm (1,210 reports)

Weight increased treatments and more:

Weight increased (279,369 reports)

Browse all side effects of Msm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Weight increased (2,887 drugs)

Browse all the conditions that are associated with Weight increased:

Weight increased (3,951 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylsulfonylmethane (the active ingredients of Msm) and Msm (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.